1232554-40-3

Basic information

• Product Name: 1-(2-isocyanophenyl)-1-butanone
• Synonyms: 1-(2-isocyanophenyl)-1-butanone
• CAS NO: 1232554-40-3
• Molecular Weight: 173.214
• Mol File: 1232554-40-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2-isocyanophenyl)-1-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-isocyanophenyl)-1-butanone(1232554-40-3)
• EPA Substance Registry System: 1-(2-isocyanophenyl)-1-butanone(1232554-40-3)

Safety Data

• Hazardous Substances Data: 1232554-40-3(Hazardous Substances Data)

Upstream product

• 2034-40-4 1-(2-aminophenyl)-1-butanone 
• 1885-29-6 anthranilic acid nitrile 
• 1232554-38-9 N-(2-butanoylphenyl)formamide 

Relevant articles and documents

Chemoselective double annulation of two different isocyanides: Rapid access to trifluoromethylated indole-fused heterocycles

An unprecedented chemoselective double annulation of α-trifluoromethylated isocyanides with o-acylaryl isocyanides has been developed. This new reaction provides a rapid, efficient, and complete atom-economic strategy for the synthesis of trifluoromethylated oxadiazino[3,2-α]indoles in a single operation from readily available starting materials. Isocyanide insertion into C=O double bonds is disclosed for the first time as indicated by the results of 18O-labeling experiment. A mechanism for this domino reaction is proposed involving chemoselective heterodimerization of two different isocyanides, followed by indole-2,3-epoxide formation and rearrangement.