1232692-96-4

Basic information

• Product Name: C₁₈H₂₅NSi
• Synonyms: C₁₈H₂₅NSi
• CAS NO: 1232692-96-4
• Molecular Weight: 283.489
• Mol File: 1232692-96-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₅NSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₅NSi(1232692-96-4)
• EPA Substance Registry System: C₁₈H₂₅NSi(1232692-96-4)

Safety Data

• Hazardous Substances Data: 1232692-96-4(Hazardous Substances Data)

Upstream product

• 2227-29-4 chlorodiisopropylsilane 
• 625-95-6 3-Iodotoluene 
• 1232692-92-0 2-(diisopropylsilyl)pyridine 
• 109-04-6 2-bromo-pyridine 
• 591-17-3 meta-bromotoluene 

Downstream Products

• 1232693-16-1 C₂₀H₂₇NO₂Si 
• 1232693-17-2 (PivO)(Me)C₆H₃Si(iPr)2C₅H₄N 
• 1260426-12-7 (CH₃)4C₂O₂BC₆H₃I(CH₃) 
• 1260426-13-8 C₁₃H₂₀FISi 
• 1260426-18-3 C₂₆H₂₉NSi 
• 35928-80-4 6-iodo-3-methyl-phenol 
• 1232693-12-7 C₂₂H₃₁NO₂Si 
• 1260425-81-7 C₁₈H₂₄BrNSi 
• 1260425-70-4 C₅H₄NSi(CH(CH₃)2)2C₆H₃I(CH₃) 

Relevant articles and documents

Pd-Catalyzed C?H Alkylation of Arenes Using PyrDipSi, a Transformable and Removable Silicon-Tethered Directing Group

An efficient Pd-catalyzed ortho-C?H alkylation reaction of arenes using a transformable and removable Si-tethered pyridyldiisopropylsilyl (PyrDipSi) directing group has been developed. In addition, the PyrDipSi directing group allows for an efficient sequential double-fold C?H alkylation/oxygenation of arenes to produce meta-alkylated phenols. This directing group can easily be removed or converted into valuable functionalities, such as aryl, iodo, boronic ester, or phenol.

PyDipSi: A general and easily modifiable/traceless Si-tethered directing group for C-H acyloxylation of arenes

A new general and easily installable silicon-tethered pyridyl-containing directing group (PyDipSi) that allows for highly efficient and regioselective Pd-catalyzed ortho C-H acyloxylation of arenes has been developed. It has also been demonstrated that this directing group can efficiently be removed as well as converted into a variety of other valuable functional groups. In addition, the installation of the PyDipSi directing group along with pivaloxylation and quantitative conversion of the PyDipSi group into a halogen functionality represents a formal three-step ortho oxygenation of haloarenes.