1232692-98-6

Basic information

• Product Name: 2-(diisopropyl(p-tolyl)silyl)pyridine
• Synonyms: 2-(diisopropyl(p-tolyl)silyl)pyridine
• CAS NO: 1232692-98-6
• Molecular Weight: 283.489
• Mol File: 1232692-98-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(diisopropyl(p-tolyl)silyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(diisopropyl(p-tolyl)silyl)pyridine(1232692-98-6)
• EPA Substance Registry System: 2-(diisopropyl(p-tolyl)silyl)pyridine(1232692-98-6)

Safety Data

• Hazardous Substances Data: 1232692-98-6(Hazardous Substances Data)

Upstream product

• 7751-38-4 Diisopropylsilyl dichloride 
• 109-04-6 2-bromo-pyridine 
• 308256-10-2 chloro-diisopropyl-p-tolyl-silane 
• 624-31-7 4-tolyl iodide 
• 2227-29-4 chlorodiisopropylsilane 
• 1232692-92-0 2-(diisopropylsilyl)pyridine 
• 106-38-7 para-bromotoluene 

Downstream Products

• 1232693-19-4 C₂₀H₂₇NO₂Si 
• 1232693-20-7 C₂₃H₃₃NO₂Si 

Relevant articles and documents

Amino acid-promoted C-H alkylation with alkylboronic acids using a removable directing group

Palladium-catalyzed C-H alkylation reaction with alkylboronic acids has successfully been developed using a removable pyridyldiisopropylsilyl directing group. The amino acid played a crucial role as a ligand in the reaction. The alkylation protocol is also applicable to the coupling of C(sp3)-H bonds with alkylboronic acids.

PyDipSi: A general and easily modifiable/traceless Si-tethered directing group for C-H acyloxylation of arenes

A new general and easily installable silicon-tethered pyridyl-containing directing group (PyDipSi) that allows for highly efficient and regioselective Pd-catalyzed ortho C-H acyloxylation of arenes has been developed. It has also been demonstrated that this directing group can efficiently be removed as well as converted into a variety of other valuable functional groups. In addition, the installation of the PyDipSi directing group along with pivaloxylation and quantitative conversion of the PyDipSi group into a halogen functionality represents a formal three-step ortho oxygenation of haloarenes.