123299-71-8Relevant articles and documents
Zinc(ii)-catalyzed Grignard additions to ketones with RMgBr and RMgI
Hatano, Manabu,Ito, Orie,Suzuki, Shinji,Ishihara, Kazuaki
supporting information; experimental part, p. 2674 - 2676 (2010/07/08)
Highly efficient alkylations and arylations of ketones with Grignard reagents (RMgBr and RMgI) have been developed using catalytic ZnCl2, Me3SiCH2MgCl, and LiCl. Tertiary alcohols were obtained in high yields with high chemoselectivities, while minimizing undesired side products produced by reduction and enolization.