1233086-44-6 Usage
General Description
1-tert-butyl 2-ethyl 5-methyl-1H-indole-1,2-dicarboxylate is a chemical compound with a complex molecular structure. It is an ester derivative of 1H-indole-1,2-dicarboxylic acid, with tert-butyl, ethyl, and methyl substituents attached to the carbon atoms. 1-tert-butyl 2-ethyl 5-methyl-1H-indole-1,2-dicarboxylate belongs to the class of organic compounds known as indole-1,2-dicarboxylate esters, which are widely used in the pharmaceutical industry for their potential therapeutic applications. The specific properties and uses of this compound may vary, but it is likely to have characteristics such as solubility in organic solvents, stability under certain conditions, and potential biological activity that make it valuable for research and development purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 1233086-44-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,3,0,8 and 6 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1233086-44:
(9*1)+(8*2)+(7*3)+(6*3)+(5*0)+(4*8)+(3*6)+(2*4)+(1*4)=126
126 % 10 = 6
So 1233086-44-6 is a valid CAS Registry Number.
1233086-44-6Relevant articles and documents
SMALL MOLECULE STAT PROTEIN DEGRADERS
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Paragraph 0997, (2021/10/02)
The present disclosure provides compounds represented by Formula (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R1a, R1b, R3a, R4, A, E1, E2, M, and Q are as set forth in the specification. Compounds of Formula (I) are STAT protein degraders and thus are useful for the treatment of cancer and other diseases.
STAT3 PROTEIN DEGRADERS
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Paragraph 0571; 0572, (2020/10/20)
The present disclosure provides compounds represented by Formulae I and IV: wherein R1a, R1b, R2a, R2b, A, E, QD, and QE are as defined in the specification, and the salts and solvates thereof. Compounds of Formula I are degraders of STAT3. Compounds of Formula IV are inhibitors of STAT3. STAT3 degraders and inhibitors are useful for the treatment of cancer and other diseases.
STAT3 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME
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Page/Page column 42, (2010/08/04)
Inhibitors of STAT3 are disclosed. Methods of using the STAT3 inhibitors in the treatment of diseases and conditions wherein inhibition of STAT3 provides a benefit, like cancers, also are disclosed.
