123314-55-6Relevant articles and documents
The Roles of the Carboxy Group in β-Lactam Antibiotics and Lysine 234 in β-Lactamase I
Laws, Andrew P.,Layland, Nicola J.,Proctor, David G.,Page, Michael I.
, p. 17 - 21 (2007/10/02)
The replacement of the C3 carboxylate in phenoxymethylpenicillin by a hydroxymethyl group and of the C4 carboxylate in cephalosporins by both a lactone and an aldehyde gives derivatives which are still good substrates for Bacillus cereus 569/H β-lactamase