1234319-81-3

Basic information

• Product Name: 2',3',5'-tri-O-acetyl-2-N-benzoyl-6-O-benzylguanosine
• Synonyms: 2',3',5'-tri-O-acetyl-2-N-benzoyl-6-O-benzylguanosine
• CAS NO: 1234319-81-3
• Molecular Weight: 603.588
• Mol File: 1234319-81-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2',3',5'-tri-O-acetyl-2-N-benzoyl-6-O-benzylguanosine(CAS DataBase Reference)
• NIST Chemistry Reference: 2',3',5'-tri-O-acetyl-2-N-benzoyl-6-O-benzylguanosine(1234319-81-3)
• EPA Substance Registry System: 2',3',5'-tri-O-acetyl-2-N-benzoyl-6-O-benzylguanosine(1234319-81-3)

Safety Data

• Hazardous Substances Data: 1234319-81-3(Hazardous Substances Data)

Upstream product

• 5987-76-8 6-chloro-2-iodo-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine 
• 1360804-45-0 C₂₃H₂₃IN₄O₈ 
• 55-21-0 benzamide 
• 16321-99-6 2-amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine 
• 1234319-76-6 6-benzyloxy-2-chloro-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine 

Downstream Products

• 66781-54-2 2',3',5'-tri-O-acetyl-N²-benzoylguanosine 

Relevant articles and documents

Pd-catalysed amidation of 2,6-dihalopurine nucleosides. Replacement of iodine at 0 °c

Pd-catalysed reactions of 2-Cl, 2-Br and 2-I derivatives of a 6-chloropurine nucleoside with benzamide have been compared, using Pd 2dba3, Xantphos and Cs2CO3 in toluene, between 20 and 80 °C. The reactivity order was 2-I > 2-Br > 6-Cl ? 2-Cl. The 2-I substituent could be replaced even at 0 °C, under conditions disclosed here for the first time. On the other hand, the replacement of the chlorine atom at position 2 (2-Cl) required 110 °C.