1234845-29-4

Basic information

• Product Name: Ethyl 2-(3-fluoro-4-methoxyphenyl)cyclopropanecarboxylate
• Synonyms: Ethyl 2-(3-fluoro-4-methoxyphenyl)cyclopropanecarboxylate
• CAS NO: 1234845-29-4
• Molecular Formula: C13H15FO3
• Molecular Weight: 238.259
• Mol File: 1234845-29-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethyl 2-(3-fluoro-4-methoxyphenyl)cyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-(3-fluoro-4-methoxyphenyl)cyclopropanecarboxylate(1234845-29-4)
• EPA Substance Registry System: Ethyl 2-(3-fluoro-4-methoxyphenyl)cyclopropanecarboxylate(1234845-29-4)

Safety Data

• Hazardous Substances Data: 1234845-29-4(Hazardous Substances Data)

Upstream product

• 351-54-2 3-fluoro-p-anisaldehyde 
• 70-25-7 N-Methyl-N'-nitro-N-nitrosoguanidine 
• 187872-44-2 ethyl (E)-3-(3-fluoro-4-methoxyphenyl)acrylate 

Downstream Products

• 1234845-30-7 2-[3-fluoro-4-hydroxyphenyl]cyclopropanecarboxylic acid ethyl ester 
• 381226-74-0 [2-(3-fluoro-4-methoxyphenyl)cyclopropyl]methanol 
• 381226-75-1 2-(3-fluoro-4-methoxyphenyl)cyclopropanecarbaldehyde 

Relevant articles and documents

THIOARYL DERIVATIVES AS GPR120 AGONISTS

The present invention relates to thioaryl derivatives of Formula 1 as defined in the specification, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The thioaryl derivatives of Formula 1 according to the present invention promote GLP-1 formation in the gastrointestinal tract and improve insulin resistance in macrophages, pancreas cells, etc. due to anti-inflammatory action, and can accordingly be effectively used for preventing or treating diabetes, complications of diabetes, inflammation, obesity, non-alcoholic fatty liver, steatohepatitis or osteoporosis.

GPR120 RECEPTOR AGONISTS AND USES THEREOF

GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.