123532-22-9

Basic information

• Product Name: 2-(1-methyl-1H-pyrazol-5-yl)phenol
• Synonyms: 2-(1-methyl-1H-pyrazol-5-yl)phenol;1-methyl-5-(2'-hydroxyphenyl)pyrazole
• CAS NO: 123532-22-9
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.1992
• Mol File: 123532-22-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(1-methyl-1H-pyrazol-5-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-methyl-1H-pyrazol-5-yl)phenol(123532-22-9)
• EPA Substance Registry System: 2-(1-methyl-1H-pyrazol-5-yl)phenol(123532-22-9)

Safety Data

• Hazardous Substances Data: 123532-22-9(Hazardous Substances Data)

Usage

General Description

2-(1-methyl-1H-pyrazol-5-yl)phenol is a chemical compound with the molecular formula C11H10N2O. It is a phenolic compound with a pyrazole ring attached to a phenol group. This chemical may have potential applications in pharmaceuticals and organic synthesis due to its unique structure and properties. It is important to handle this chemical with caution and proper safety measures, as it can be hazardous if not handled properly. Its potential uses and properties make it an interesting compound for further research and development.

Upstream product

• 491-38-3 1-benzopyran-4(4H)-one 
• 33533-81-2 N-<2-(2-hydroxybenzoyl)vinyl>-pyrrolizidine 
• 60-34-4 methylhydrazine 
• 123532-14-9 N₁-2-(2-hydroxybenzoyl)vinyl-N₁-methylhydrazine 
• 87059-79-8 2-hydroxy-α-(hydroxymethylene)acetophenone 
• 6005-15-8 thiochromone 

Downstream Products

• 1235395-34-2 3-fluoro-4-(2-(1-methyl-1H-pyrazol-5-yl)phenoxy)-N-(thiazol-2-yl)benzenesulfonamide 
• 140226-35-3 1-methyl-5-(2'-methoxyphenyl)pyrazole 

Relevant articles and documents

New ultraviolet stabilizers: 3- and 5-(2′-hydroxyphenyl)pyrazoles

A new class of ultraviolet stabilizers, the C-(2?-hydroxyphenyl)pyrazoles, is described. The combined use of X-ray crystallography [3(5)-(2′-hydroxyphenyl)pyrazole (5), l-methyl-3-(2′-hydroxyphenyl)pyrazole (7), and 1-methyl-5-(2?-hydroxyphenyl)pyrazole (8)], NMR (1 and 13C), and UV spectroscopies allows the determination of the major tautomers, the coplanarity of both rings if present, and the existence of hydrogen bonds. Compounds 5 and 7, in which there is an intramolecular hydrogen bond (IMHB), do not fluoresce in cyclohexane. Solvent and temperature experiments prove that for these compounds in cyclohexane proton transfer took place in the excited singlet state but not in the triplet state (phosphorescence) and that the latter one is of higher energy than the former. The fact that the absorptions of planar 1-methyl-3-(2′-methoxyphenyl)pyrazole (9) and nonplanar 1-methyl-5-(2′-methoxyphenyl)pyrazole (10) are quite different whereas their emissions are very similar suggests that 10 might behave as a laser dye in the UV region (from an excited planar form to a ground state nonplanar form). Finally, the photostability of (2'-hydroxyphenyl)- and (2′-methoxyphenyl)pyrazoles was determined, compound 7 being even more stable than Tinuvin P.

STUDIES OF CHROMONE DERIVATIVES. PART XV. REACTIONS OF CHROMONE AND ITS DERIVATIVES WITH METHYLHYDRAZINE

The transformations of chromone, 6-methyl-, 6-nitro-, and 8-methylchromone with methylhydrazine have been studied.Two series of pyrazoles (A and B) were obtained and transformation intermediates have been isolated.The structure of these compounds has been established and the reaction course of chromone and its derivatives with methylhydrazine is proposed.