1236033-03-6 Usage
General Description
The chemical "1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-[7-(hydroxyMethyl)-7H-pyrrolo[2,3-d]pyriMidin-4-yl]-,(βR)-" is a complex compound characterized by its structural arrangement and properties. It is a pyrazole derivative with a cyclopentyl and pyrrolidine ring system, and a nitrile functional group. It also contains a hydroxymethyl and pyrimidinyl group. The stereochemistry is specified as βR, indicating the configuration of the molecule. 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-[7-(hydroxyMethyl)-7H-pyrrolo[2,3-d]pyriMidin-4-yl]-,(βR)- may have potential applications in pharmaceutical and medicinal chemistry due to its unique structure and functional groups, which could make it a valuable candidate for drug development and research.
Check Digit Verification of cas no
The CAS Registry Mumber 1236033-03-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,6,0,3 and 3 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1236033-03:
(9*1)+(8*2)+(7*3)+(6*6)+(5*0)+(4*3)+(3*3)+(2*0)+(1*3)=106
106 % 10 = 6
So 1236033-03-6 is a valid CAS Registry Number.
1236033-03-6Relevant articles and documents
Enantioselective synthesis of janus kinase inhibitor INCB018424 via an organocatalytic aza-michael reaction
Lin, Qiyan,Meloni, David,Pan, Yongchun,Xia, Michael,Rodgers, James,Shepard, Stacey,Li, Mei,Galya, Laurine,Metcalf, Brian,Yue, Tai-N,Liu, Pingli,Zhou, Jiacheng
, p. 1999 - 2002 (2009)
An enantioselective synthesis of INCB018424 via organocatalytic asymmetric aza-Michael addition of pyrazoles (16 or 20) to (E)-3- cyclopentylacrylaldehyde (23) using diarylprolinol silyl ether as the catalyst was developed. Michael adducts (R)-24 and (R)-27 were isolated in good yield and high ee and were readily converted to INCB018424.
