1236131-38-6

Basic information

• Product Name: (Z)-2-phenyl-6-(pyrrolidin-1-yl)hex-2-enenitrile
• Synonyms: (Z)-2-phenyl-6-(pyrrolidin-1-yl)hex-2-enenitrile
• CAS NO: 1236131-38-6
• Molecular Weight: 240.348
• Mol File: 1236131-38-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-2-phenyl-6-(pyrrolidin-1-yl)hex-2-enenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-phenyl-6-(pyrrolidin-1-yl)hex-2-enenitrile(1236131-38-6)
• EPA Substance Registry System: (Z)-2-phenyl-6-(pyrrolidin-1-yl)hex-2-enenitrile(1236131-38-6)

Safety Data

• Hazardous Substances Data: 1236131-38-6(Hazardous Substances Data)

Upstream product

• 35543-25-0 4-(pyrrolidin-1-yl)butyronitrile 
• 536-74-3 phenylacetylene 

Relevant articles and documents

Heteroatom-directed alkylcyanation of alkynes

Alkanenitriles having a heteroatom such as nitrogen, oxygen, and sulfur at the γ-position are found to add across alkynes stereo-and regioselectively by nickel/Lewis acid catalysis to give highly substituted acrylonitriles. The heteroatom functionalities likely coordinate to the nickel center to make oxidative addition of the C-CN bonds of the alkyl cyanides kinetically favorable, forming a five-membered nickelacycle intermediate and, thus, preventing β-hydride elimination to allow the alkylcyanation reaction.