123673-31-4Relevant articles and documents
INHIBITING B-CELL LYMPHOMA 2 (BCL-2) AND RELATED PROTEINS
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Paragraph 00125, (2017/09/05)
Novel compounds inhibiting anti-apoptosis proteins B-cell lymphoma 2 (Bcl-2) and Bcl-XL include compounds of formula (I) and formula (II) disclosed herein, as well as liposome compositions comprising Bcl-2 inhibitor compounds. These compositions are usefu
Highly Diastereoselective 1,4-Addition of Amines to Chiral α,β-Unsaturated δ-Lactone
Yoda, Hidemi,Shirai, Tsuyoshi,Kawasaki, Tomoyasu,Katagiri, Takao,Takabe, Kunihiko,et al.
, p. 793 - 794 (2007/10/02)
Michael addition of amines to (S)-γ-amino-α,β-unsaturated δ-lactones was accomplished in extremely high diastereoselectivity with the ring-opening reactions and was disclosed to furnish (3R,4S)-diamino-hydroxyamides in high yields.
Selective Reduction of Nα-Protected Dicarboxylic Amino Acid Anhydrides into Corresponding Protected Amino Alcohols
Kundu, B.,Srivastava, V. P.,Mathur, K. B.
, p. 1124 (2007/10/02)
Nα-Protected dicarboxylic amino acid anhydrides, such as those of Z-D-Asp or Z-D-Glu have been selectively reduced in excellent yields with NaBH4 to give the corresponding Nα-protected amino alcohols.A probable mechanism for the sele