123694-54-2Relevant articles and documents
Synthesis and hypolipidemic activity of diesters of arylnaphthalene lignan and their heteroaromatic analogs
Kuroda, Tooru,Kondo, Kazuhiko,Iwasaki, Tameo,Ohtani, Akio,Takashima, Kohki
, p. 678 - 684 (2007/10/03)
A series of diesters of arylnaphthalene lignan and their heteroaromatic analogs were synthesized and evaluated for hypolipidemic activity. The diesters with modifications at C-3 showed excellent hypocholesterolemic and high-density lipoprotein (HDL) cholesterol-elevating activities. Structure- activity analysis indicated that the 2-pyridylmethyl ester 51 has the optimum activity.
Phenyl benzothiophene hypolipidemic derivatives
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, (2008/06/13)
Biphenyl derivative of the formula: STR1 wherein R1 is hydrogen atom or a lower alkoxycarbonyl group and R2 is a lower alkoxycarbonyl group, or R1 and R2 are combined together to form a group of the formula: eac