1240081-12-2

Basic information

• Product Name: C₁₁H₁₆O₄
• Synonyms: C₁₁H₁₆O₄
• CAS NO: 1240081-12-2
• Molecular Weight: 212.246
• Mol File: 1240081-12-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₆O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₆O₄(1240081-12-2)
• EPA Substance Registry System: C₁₁H₁₆O₄(1240081-12-2)

Safety Data

• Hazardous Substances Data: 1240081-12-2(Hazardous Substances Data)

Upstream product

• 58529-72-9 3-isopropoxycyclohex-2-en-1-one 
• 79-22-1 methyl chloroformate 

Downstream Products

• 1240081-14-4 C₁₄H₂₀O₄ 

Relevant articles and documents

Recombination of diterpenoid structure units: Synthesis of antitumor amides bearing functionalized bicyclo[3.2.1]octane ring

In this work, 23 new amides (14-36) bearing a representative diterpenoid structure unit, the functionalized bicyclo[3.2.1]octane ring, have been synthesized and its antitumor potential is studied. In vitro studies demonstrate that a number of amides with the bicyclo[3.2.1]oct-3-en-2-one subunit are active against HL-60, SMMC-7721, A-549, SK-BR-3, and PANC-1 tumor cell lines. The hybrid derivative, compound 20, was found to be the most potent compound (IC50 = 1.05 μM against HL-60) and more active than cisplatin (DDP), the positive control. Additionally, compound 20 exhibited broad spectrum in vitro anticancer activity with IC50 values of 1.1-4.3 μM against the five tested cancer cell lines.