1240388-89-9

Basic information

• Product Name: 1-(4-(methylsulfonyl)phenyl)ethanone-O-methyl oxime
• Synonyms: 1-(4-(methylsulfonyl)phenyl)ethanone-O-methyl oxime
• CAS NO: 1240388-89-9
• Molecular Weight: 227.284
• Mol File: 1240388-89-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-(4-(methylsulfonyl)phenyl)ethanone-O-methyl oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(methylsulfonyl)phenyl)ethanone-O-methyl oxime(1240388-89-9)
• EPA Substance Registry System: 1-(4-(methylsulfonyl)phenyl)ethanone-O-methyl oxime(1240388-89-9)

Safety Data

• Hazardous Substances Data: 1240388-89-9(Hazardous Substances Data)

Upstream product

• 10297-73-1 4-(methanesulfonyl)acetophenone 
• 593-56-6 N-methoxylamine hydrochloride 
• 2446-51-7 N-methoxybenzamide 

Downstream Products

• 1240389-18-7 C₁₇H₁₆FNO₄S 
• 1448171-24-1 C₁₅H₂₂N₂O₃S 
• 1393678-51-7 dimethyl 2-(2-((E)-1-methoxyiminoethyl)-5-(methylsulfonyl)phenyl)malonate 

Relevant articles and documents

Nitrate promoted mild and versatile Pd-catalysed C(sp2)-H oxidation with carboxylic acids

A nitrate-promoted Pd-catalysed mild cross-dehydrogenative C(sp2)-H bond oxidation of oximes or azobenzenes with diverse carboxylic acids has been developed. In contrast to the previous catalytic systems, this protocol features mild conditions (close to room temperature for most cases) and a broad substrate scope (up to 64 examples), thus constituting a versatile method to directly prepare diverse O-aryl esters. Moreover, the superiority of the nitrate additive in this mild transformation was further determined by experimental and computational evidence.

Method for synthesizing oxime ether compound based on C-N bond breakage

The invention relates to a method for synthesizing an oxime ether compound based on C-N bond breakage. The method comprises the step of making a compound shown in equation (1) and a compound show in equation (2) react in the presence of peroxide and an organic solvent to obtain the oxime ether compound as shown in formula (3), and reaction expression is shown in the description. According to the method, synthesis path is short, starting materials are simple, reaction condition is mild, the peroxide is cheap and free of pollution, substrate range is wide, products are easy to separate, and adaptability is high when reaction is amplified to be at the gram grade.

[Cp*RhCl2]2-catalyzed ortho-C-H bond amination of acetophenone o-methyloximes with primary N-chloroalkylamines: Convenient synthesis of N-alkyl-2-acylanilines

Rh(iii)-catalyzed aromatic C-H amination of acetophenone o-methyloximes with primary N-chloroalkylamines was developed, and the arylamine products were obtained in up to 92% yield. The reaction probably involves rate-limiting electrophilic C-H bond cleavage (kH/kD = 2).