124041-74-3

Basic information

• Product Name: 2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethan-1-one
• Synonyms: 2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethan-1-one
• CAS NO: 124041-74-3
• Molecular Weight: 271.706
• Mol File: 124041-74-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethan-1-one(124041-74-3)
• EPA Substance Registry System: 2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethan-1-one(124041-74-3)

Safety Data

• Hazardous Substances Data: 124041-74-3(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 99-91-2 para-chloroacetophenone 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 937-20-2 p-chlorophenacyl chloride 
• 26086-60-2 2-azido-4'-chloroacetophenone 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 122-01-0 4-chloro-benzoyl chloride 
• 122296-00-8 1-<(trimethylsilyl)methyl>benzotriazole 

Downstream Products

• 1375797-46-8 1-(2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethylidene)-2-(4-(3,5-bis(trifluoromethyl)phenyl)thiazol-2-yl)hydrazine 
• 1375797-45-7 1-(2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethylidene)-2-(4-(4-nitrophenyl)thiazol-2-yl)hydrazine 
• 875759-16-3 1-(2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethylidene)-2-(4-(4-bromophenyl)thiazol-2-yl)hydrazine 
• 875759-17-4 1-(2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethylidene)-2-(4-(4-chlorophenyl)thiazol-2-yl)hydrazine 
• 1375797-44-6 1-(2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethylidene)-2-(4-(4-fluorophenyl)thiazol-2-yl)hydrazine 
• 875759-21-0 1-(2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethylidene)thiosemicarbazide 
• 14062-24-9 4-chloro-benzeneacetic acid, ethyl ester 
• 635303-48-9 1-[3-(4-chlorophenyl)-2H-aziren-2-yl]-1H-1,2,3-benzotriazole 
• 124041-70-9 2-(1H-1,2,3-benzotriazol-1-yl)-1-(4-chlorophenyl)-1-ethanone oxime 
• 361379-15-9 (Z)-2-(1H-1,2,3-benzotriazol-1-yl)-1-(4-chlorophenyl)ethenyl trifluoromethanesulfonate 
• 314765-27-0 (E)-2-(1H-1,2,3-benzotriazol-1-yl)-1-(4-chlorophenyl)ethenyl trifluoromethanesulfonate 
• 72673-14-4 2,4-Bis(4-chlorophenyl)-6-phenylpyridine 

Relevant articles and documents

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Microwave-assisted benzyne-click chemistry: preparation of 1H-benzo[d][1,2,3]triazoles

The benzotriazoles were prepared by three-component and two-component microwave-assisted [3+2] cycloadditions of various azides to benzyne, 3-methoxybenzyne, and 4,5-difluorobenzyne. In the three-component reaction, the aryne is generated, in the presence of an azide prepared in situ, by the reaction of an o-(trimethylsilylaryl) triflate with either CsF or KF/18-Crown-6. However, in the two-component reactions, a freshly prepared azide is added to the reaction vessel prior to aryne generation. Good to excellent yields of benzotriazoles were obtained in 15-20 min when the microwave-assisted reactions were carried out at 125 °C. These reaction times are significantly faster than similar reactions carried out using conventional heating.