1240659-41-9Relevant articles and documents
Fe(II)-catalyzed amination of aromatic C-H bonds via ring opening of 2 H-azirines: Synthesis of 2,3-disubstituted indoles
Jana, Samaresh,Clements, MacK D.,Sharp, Barry K.,Zheng, Nan
supporting information; experimental part, p. 3736 - 3739 (2010/11/03)
A general method for the synthesis of 2,3-disubstituted indoles is described. The key feature of this method is the amination of aromatic C-H bonds via FeCl2-catalyzed ring opening of 2H-azirines. The method tolerates a variety of functional groups such as Br, F, NO2, OMe, CF3, OTBS, alkenes, and OPiv. The method can also be extended to synthesize azaindoles.