124096-49-7

Basic information

• Product Name: (S)-1-((E)-2-Phenyl-propenyl)-pyrrolidine-2-carboxylic acid ethyl ester
• CAS NO: 124096-49-7
• Molecular Weight: 259.348
• Mol File: 124096-49-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-((E)-2-Phenyl-propenyl)-pyrrolidine-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-((E)-2-Phenyl-propenyl)-pyrrolidine-2-carboxylic acid ethyl ester(124096-49-7)
• EPA Substance Registry System: (S)-1-((E)-2-Phenyl-propenyl)-pyrrolidine-2-carboxylic acid ethyl ester(124096-49-7)

Safety Data

• Hazardous Substances Data: 124096-49-7(Hazardous Substances Data)

Upstream product

• 34713-70-7 2-Phenylpropanal 
• 5817-26-5 ethyl (2S)-pyrrolidine-2-carboxylate 

Relevant articles and documents

The palladium-catalyzed asymmetric α-allylations of carbonyl compounds with chiral allyl esters via enamines and imines

A novel and excellent method for asymmetric α-allylation of carbonyl compounds via their chiral enamines or imines bearing allyl esters has been developed. Readily available chiral allyl esters having chirality at the α- position of the ester carbonyl group, such as (S)-proline and other (S)-α- amino acid allyl esters, have been found to serve as good asymmetric allylating reagents in palladium-catalyzed reactions of the chiral enamines and imines derived from them. The use of (S)-proline or (S)-valine allyl esters as the amino parts in the enamines or imines provided the highest optical yields of the corresponding α-allyl carbonyl compounds. A mechanism for asymmetric induction is proposed based on the stereochemical results obtained.