1241572-89-3

Basic information

• Product Name: 1-pentafluorophenyl-2-propyn-1-ol
• Synonyms: 1-pentafluorophenyl-2-propyn-1-ol
• CAS NO: 1241572-89-3
• Molecular Weight: 222.114
• Mol File: 1241572-89-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-pentafluorophenyl-2-propyn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-pentafluorophenyl-2-propyn-1-ol(1241572-89-3)
• EPA Substance Registry System: 1-pentafluorophenyl-2-propyn-1-ol(1241572-89-3)

Safety Data

• Hazardous Substances Data: 1241572-89-3(Hazardous Substances Data)

Upstream product

• 653-37-2 perfluorobenzaldehyde 
• 4301-14-8 acetylenemagnesium bromide 

Downstream Products

• 653-34-9 2,3,4,5,6-pentafluorostyrene 
• 1241573-16-9 1-pentafluorophenyl-2-oxopropyl benzoate 
• 1427777-88-5 C₁₄H₈F₈O₅S 

Relevant articles and documents

Axial-to-Central Chirality Transfer for Construction of Quaternary Stereocenters via Dearomatization of BINOLs

All-carbon quaternary stereocenters are versatile building blocks, and their asymmetric construction has attracted much attention. Herein, we disclose an axial-to-central chirality transfer strategy for the synthesis of chiral quaternary stereocenters via dearomatization of (S)-BINOLs. The reaction proceeded smoothly with a wide range of propargyl carbonates to afford chiral spiro-compounds in high yields with excellent enantioselectivities. In addition, the strategy was extended to kinetic resolution of rac-BINOLs albeit with moderate s value.