124167-45-9 Usage
Description
4-Methylumbelliferyl 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside, with the CAS number 124167-45-9, is a white solid compound that is primarily utilized in organic synthesis. It is a derivative of a glucopyranoside, which is a type of sugar molecule, and features a methylumbelliferyl group attached to it. 4-Methylumbelliferyl2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is known for its unique chemical properties and potential applications in various fields.
Uses
Used in Organic Synthesis:
4-Methylumbelliferyl 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is used as an intermediate in organic synthesis for the production of various complex organic molecules. Its unique structure allows it to be a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Methylumbelliferyl 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is used as a key component in the development of new drugs. Its specific chemical properties make it suitable for the creation of novel drug candidates with potential therapeutic applications.
Used in Research and Development:
4-Methylumbelliferyl2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is also used in research and development laboratories for studying the chemical properties and reactivity of similar sugar-based molecules. It can be employed as a reference material or a starting point for the synthesis of new compounds with potential applications in various fields.
Used in Analytical Chemistry:
4-Methylumbelliferyl 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside can be used as a standard or a reference compound in analytical chemistry. Its well-defined structure and properties make it suitable for calibrating instruments and developing new analytical methods for the characterization of similar compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 124167-45-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,1,6 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 124167-45:
(8*1)+(7*2)+(6*4)+(5*1)+(4*6)+(3*7)+(2*4)+(1*5)=109
109 % 10 = 9
So 124167-45-9 is a valid CAS Registry Number.
124167-45-9Relevant articles and documents
Synthesis and Characterization of Versatile O-Glycan Precursors for Cellular O-Glycomics
Zhang, Qing,Li, Zhonghua,Chernova, Tatiana,Saikam, Varma,Cummings, Richard,Song, Xuezheng,Ju, Tongzhong,Smith, David F.,Wang, Peng G.
, p. 2507 - 2513 (2019)
Protein O-glycosylation is a universal post-translational modification and plays essential roles in many biological processes. Recently we reported a technology termed cellular O-glycome reporter/amplification (CORA) to amplify and profile mucin-type O-glycans of living cells growing in the presence of peracetylated Benzyl-α-GalNAc (Ac3GalNAc-α-Bn). However, the application and development of the CORA method are limited by the properties of the precursor benzyl aglycone, which is relatively inert to further chemical modifications. Here we described a rapid parallel microwave-assisted synthesis of Ac3GalNAc-α-Bn derivatives to identify versatile precursors for cellular O-glycomics. In total, 26 derivatives, including fluorescent and bioorthogonal reactive ones, were successfully synthesized. The precursors were evaluated for their activity as acceptors for T-synthase and for their ability to function as CORA precursors. Several of the precursors possessing useful functional groups were more efficient than Ac3GalNAc-α-Bn as T-synthase acceptors and cellular O-glycome reporters. These precursors will advance the CORA technology for studies of functional O-glycomics.
