1241731-94-1Relevant articles and documents
Construction of enantioenriched cyclic compounds by asymmetric allylic alkylation and ring-closing metathesis
Giacomina, Francesca,Alexakis, Alexandre
supporting information, p. 6710 - 6721 (2013/11/06)
A new approach to highly enantioenriched cyclic compounds (up to 98a€‰% ee) has been developed by using ω-ethylenic allylic substrates in a one-pot asymmetric allylic alkylation and ring-closing metathesis sequence. The starting compounds are synthetic equivalents of cyclic allylic substrates. The method is exemplified with both Cu and Ir catalysts, and chiral phosphoramidite ligands. A new approach to highly enantioenriched cyclic compounds (up to 98a€‰% ee) has been developed by using ω-ethylenic allylic substrates in a one-pot asymmetric allylic alkylation and ring-closing metathesis sequence. The starting compounds are synthetic equivalents of cyclic allylic substrates. The method is exemplified with both Cu and Ir catalysts, and chiral phosphoramidite ligands. Copyright
ω-Ethylenic allylic substrates as alternatives to cyclic substrates in copper- and iridium-catalyzed asymmetric allylic alkylation
Giacomina, Francesca,Riat, David,Alexakis, Alexandre
supporting information; experimental part, p. 1156 - 1159 (2010/05/18)
"Chemical Equation Presented" A new strategy to access highly enantioenriched cyclic compounds (up to 98%) Is proposed using ω-ethylenic allylic substrates through a one-pot asymmetric allylic alkylation and ring-closing metathesis. Such starting compounds can be seen as synthetic equivalents of cyclic allylic substrates.
