124211-85-4

Basic information

• Product Name: 2-phenyl-4-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinylamino)methylene-5(4H)-oxazolone
• Synonyms: 2-phenyl-4-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinylamino)methylene-5(4H)-oxazolone
• CAS NO: 124211-85-4
• Molecular Weight: 384.415
• Mol File: 124211-85-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-phenyl-4-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinylamino)methylene-5(4H)-oxazolone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-4-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinylamino)methylene-5(4H)-oxazolone(124211-85-4)
• EPA Substance Registry System: 2-phenyl-4-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinylamino)methylene-5(4H)-oxazolone(124211-85-4)

Safety Data

• Hazardous Substances Data: 124211-85-4(Hazardous Substances Data)

Upstream product

• 776-53-4 ethyl 4-amino-2-methylmercaptopyrimidine-5-carboxylate 
• 1199-01-5 2-phenylazlactone 
• 124211-81-0 4-(Dimethylamino-methyleneamino)-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester 

Downstream Products

• 124232-36-6 (Z)-2-benzoylamino-3-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinyl)aminopropenoylhydrazide 
• 124212-01-7 (Z)-2-benzoylamino-3-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinyl)aminopropenamide 
• 124212-26-6 2-benzoylamino-3-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinyl)aminopropanamide 
• 124212-20-0 2-benzoylamino-3-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinyl)aminopropanol 
• 124211-98-9 ethyl (Z)-2-benzoylamino-3-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinyl)aminopropenoate 
• 124211-93-4 methyl (Z)-2-benzoylamino-3-(5-ethoxycarbonyl-2-methylthio-4-pyrimidinyl)aminopropenoate 

Relevant articles and documents

The transformations of 4-heteroarylaminomethylene-5(4H)-oxazolones into dehydropeptide derivatives

2-Phenyl-4-heteroarylaminomethylene-5(4H)-oxazolones 3, which were prepared from the corresponding N,N-dimethyl-N'-heteroarylformamidines 1 and hippuric acid 2 in acetic anhydride, react with amino acids giving dehydropeptide derivatives 4, 5, and 6 as products. Dehydration of N-protected peptides 7-10, containing glycine at the C-terminal, followed by the reaction with formamidines 1 gave 2-substituted-4-heteroarylaminomethylene-5(4H)-oxazolones 11-14.