1242175-38-7 Usage
Description
(2S,3S)-2-[(1S)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy]-3-(4-fluorophenyl)morpholine, also known as (S,S)-2-((S)-1-(3,5-bis-trifluoromethylphenyl)ethoxy)-4-phenylmorpholine, is a complex organic compound characterized by a morpholine backbone and two distinct substituent groups. One of these groups is a fluorophenyl moiety, while the other is an (S)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy group. The stereochemistry of this compound is crucial for its biological activity, and it is recognized for its potential applications in pharmaceuticals and research. It is particularly noted for its utility as a chiral auxiliary in asymmetric synthesis and as a ligand in transition metal catalysis reactions, where it aids in achieving stereocontrolled outcomes. The unique structural attributes and properties of this compound render it a valuable asset in the realm of organic chemistry.
Uses
Used in Pharmaceutical Industry:
(2S,3S)-2-[(1S)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy]-3-(4-fluorophenyl)morpholine is used as a chiral auxiliary for enhancing the selectivity and yield of enantioselective reactions in the synthesis of pharmaceutical compounds. Its precise stereochemistry allows for the creation of biologically active molecules with desired properties.
Used in Research Applications:
In the research field, (2S,3S)-2-[(1S)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy]-3-(4-fluorophenyl)morpholine serves as a valuable tool for studying asymmetric synthesis and the development of novel synthetic methodologies. Its use can lead to a better understanding of stereoselective reactions and the creation of enantiomerically pure compounds.
Used in Asymmetric Synthesis:
(2S,3S)-2-[(1S)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy]-3-(4-fluorophenyl)morpholine is utilized as a chiral auxiliary in asymmetric synthesis to control the stereochemistry of the products formed. This is particularly important in the synthesis of complex molecules with multiple chiral centers, where the compound's stereochemistry can guide the formation of specific enantiomers.
Used in Transition Metal Catalysis:
As a ligand in transition metal catalysis reactions, (2S,3S)-2-[(1S)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy]-3-(4-fluorophenyl)morpholine is instrumental in facilitating stereocontrolled reactions. Its unique structure allows it to interact with metal centers, influencing the selectivity and efficiency of catalytic processes.
Used in Organic Chemistry:
In the broader field of organic chemistry, (2S,3S)-2-[(1S)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy]-3-(4-fluorophenyl)morpholine is employed for its potential in various applications, including the development of new synthetic routes, the study of reaction mechanisms, and the creation of novel compounds with specific properties. Its unique structure and properties make it a compound of interest for chemists exploring the frontiers of organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1242175-38-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,2,1,7 and 5 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1242175-38:
(9*1)+(8*2)+(7*4)+(6*2)+(5*1)+(4*7)+(3*5)+(2*3)+(1*8)=127
127 % 10 = 7
So 1242175-38-7 is a valid CAS Registry Number.
1242175-38-7Relevant articles and documents
Synthesis of all enantiomerically pure diastereomers of aprepitant
Gangula, Srinivas,Elati, Chandrashekhar R.,Mudunuru, Satish Varma,Nardela, Anitha,Dongamanti, Ashok,Bhattacharya, Apurba,Bandichhor, Rakeshwar
experimental part, p. 2254 - 2268 (2010/09/11)
Syntheses of all eight enantiomerically pure diastereomers of aprepitant and assignment of absolute configuration at newly generated stereocenters by NMR and X-ray crystallographic analysis were achieved. Copyrigh
