124225-33-8Relevant articles and documents
Cubanes in medicinal chemistry: Synthesis of functionalized building blocks
Wlochal, Joanna,Davies, Robert D. M.,Burton, Jonathan
supporting information, p. 4094 - 4097 (2014/09/29)
A collection of novel, pharmaceutically relevant cubane-containing molecules has been prepared from the commercially available cubane-1,4- dimethylester. A range of synthetic methods have been applied to prepare these cubane building blocks with one or two functional handles to allow easy incorporation into existing medicinal chemistry programs.
4-Substituted cubylcarbinylamines: A new class of mechanism-based monoamine oxidase B inactivators
Zhou,Li,Upadhyaya,Eaton,Silverman
, p. 1165 - 1168 (2007/10/03)
Cubylcarbinylamine (1a), (4-cyclopropylcubyl)carbinylamine (1b), and (4- phenylcubyl)carbinylamine (1c) were synthesized and shown to be time- dependent, irreversible inactivators of monoamine oxidase B (MAO B). Substrate protects the enzyme from inactiva
The reactions of 1,4-dihalocubanes with organolithiums. The case for 1,4-cubadiyl
Eaton,Tsanaktsidis
, p. 876 - 878 (2007/10/02)
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