1242440-98-7

Basic information

• Product Name: (1S,2S)-ethyl 2-(4-(1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate
• Synonyms: (1S,2S)-ethyl 2-(4-(1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate
• CAS NO: 1242440-98-7
• Molecular Weight: 256.304
• Mol File: 1242440-98-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,2S)-ethyl 2-(4-(1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S)-ethyl 2-(4-(1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate(1242440-98-7)
• EPA Substance Registry System: (1S,2S)-ethyl 2-(4-(1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate(1242440-98-7)

Safety Data

• Hazardous Substances Data: 1242440-98-7(Hazardous Substances Data)

Usage

Description

(1S,2S)-ethyl 2-(4-(1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate is a chemical compound with the molecular formula C17H18N2O2. It is an ester that features a cyclopropane ring and an imidazole group. (1S,2S)-ethyl 2-(4-(1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate holds potential pharmaceutical applications due to its ability to interact with biological targets and pathways, which may be instrumental in addressing a range of conditions such as neurological disorders and cancer.

Uses

Used in Pharmaceutical Industry:
(1S,2S)-ethyl 2-(4-(1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate is used as a potential therapeutic agent for the treatment of neurological disorders and cancer. Its unique structure allows it to engage with specific biological targets and pathways, offering a new avenue for the development of treatments in these areas.
However, it is important to note that more research is required to fully understand the compound's potential uses and effects, as well as to establish its safety and efficacy profile. This will involve extensive preclinical and clinical studies to determine the optimal dosage, delivery methods, and potential side effects before it can be considered for widespread use in medical treatments.

Upstream product

• 875479-34-8 ethyl trans-2-(4-bromophenyl)cyclopropane-1-carboxylate 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 1242440-99-8 (1S,2S)-ethyl 2-(4-(1-trityl-1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate 

Downstream Products

• 1242441-15-1 ethyl (1S,2S)-2-{4-[1-(2-fluoroethyl)-1H-imidazol-4-yl]phenyl}cyclopropanecarboxylate 
• 1319211-95-4 (1S,2S)-ethyl 2-(4-(5-iodo-1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate 
• 1242441-48-0 (1S,2S)-ethyl 2-(4-(5-((5-chloropyridin-2-yl)thio)-1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate 
• 1242441-49-1 (1S,2S)-2-(4-(5-((5-chloropyridin-2-yl)thio)-1H-imidazol-4-yl)phenyl)cyclopropanecarboxylic acid 
• 1242441-14-0 ethyl (1S,2S)-2-{4-[1-(2-fluoroethyl)-5-iodo-1H-imidazol-4-yl]phenyl}cyclopropanecarboxylate 
• 1242441-56-0 [³H]-(1S,2S)-2-(4-{5-[(5-chloropyridin-2-yl)thio]-1-methyl-1H-imidazol-4-yl}phenyl)-N,Ndimethylcyclopropanecarboxamide 
• 1242441-47-9 (1S,2S)-2-(4-(5-((5-chloropyridin-2-yl)thio)-1H-imidazol-4-yl)phenyl)-N,Ndimethylcyclopropanecarboxamide 
• 1242441-39-9 C₂₀H₁₇ClFN₃O₂S 
• 1242441-37-7 (1S,2S)-2-(4-(5-((5-chloropyridin-2-yl)thio)-1-(2-fluoroethyl)-1H-imidazol-4-yl)phenyl)-N,Ndimethylcyclopropanecarboxamide 

Relevant articles and documents

Discovery of MK-3168: A PET tracer for imaging brain fatty acid amide hydrolase

We report herein the discovery of a fatty acid amide hydrolase (FAAH) positron emission tomography (PET) tracer. Starting from a pyrazole lead, medicinal chemistry efforts directed toward reducing lipophilicity led to the synthesis of a series of imidazole analogues. Compound 6 was chosen for further profiling due to its appropriate physical chemical properties and excellent FAAH inhibition potency across species. [11C]-6 (MK-3168) exhibited good brain uptake and FAAH-specific signal in rhesus monkeys and is a suitable PET tracer for imaging FAAH in the brain.