124251-84-9

Basic information

• Product Name: 1-NAPHTHOL-2,3,4,5,6,7,8-D7
• Synonyms: 1-NAPHTHOL-2,3,4,5,6,7,8-D7;1-NAPHTHOL-D7;1-NAPHTHOL-2,3,4,5,6,7,8-D7, 97 ATOM % D;1-NAPHTHOL-D7 98%;1-Naphthol-d7 (d6 Major);2,3,4,5,6,7,8-heptadeuterionaphthalen-1-ol
• CAS NO: 124251-84-9
• Molecular Formula: C10HD7O
• Molecular Weight: 151.21
• Product Categories: Alphabetical Listings;N-O;Stable Isotopes
• Mol File: 124251-84-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 94-96 °C(lit.)
• Boiling Point: 278-280 °C(lit.)
• Flash Point: 144°C
• Appearance: /
• Density: 1.239g/cm³
• Vapor Pressure: 0.00139mmHg at 25°C
• Refractive Index: 1.677
• CAS DataBase Reference: 1-NAPHTHOL-2,3,4,5,6,7,8-D7(CAS DataBase Reference)
• NIST Chemistry Reference: 1-NAPHTHOL-2,3,4,5,6,7,8-D7(124251-84-9)
• EPA Substance Registry System: 1-NAPHTHOL-2,3,4,5,6,7,8-D7(124251-84-9)

Safety Data

• Hazard Codes: Xn
• Statements: 21/22-37/38-41
• Safety Statements: 22-26-37/39
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 124251-84-9(Hazardous Substances Data)

Usage

Description

1-NAPHTHOL-2,3,4,5,6,7,8-D7 is a deuterated analog of 1-Naphthol, a compound that is widely used in the production of dyes, intermediates, and synthetic perfumes. The incorporation of deuterium atoms in the molecule enhances its stability and provides unique properties for specific applications.

Uses

Used in Chemical Synthesis Industry:
1-NAPHTHOL-2,3,4,5,6,7,8-D7 is used as a stable isotope labeled compound for the synthesis of deuterated dyes and intermediates. The presence of deuterium atoms in the molecule improves the stability and reactivity of the synthesized products, making them suitable for various applications.
Used in Perfume Industry:
1-NAPHTHOL-2,3,4,5,6,7,8-D7 is used as a deuterated analog of 1-Naphthol in the production of synthetic perfumes. The deuterium labeling provides enhanced stability and longevity to the fragrance, ensuring a longer-lasting scent.
Used in Research and Development:
1-NAPHTHOL-2,3,4,5,6,7,8-D7 is used as a research tool in the development of new dyes, intermediates, and synthetic perfumes. The deuterium labeling allows for the study of the compound's properties and behavior under various conditions, aiding in the optimization of synthesis processes and the discovery of new applications.
Used in Analytical Chemistry:
1-NAPHTHOL-2,3,4,5,6,7,8-D7 is used as an internal standard or a tracer in analytical chemistry for the accurate quantification and identification of related compounds. The presence of deuterium atoms provides a distinct mass signature, facilitating the differentiation and quantification of target analytes in complex samples.

InChI:InChI=1/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H/i1D,2D,3D,4D,5D,6D,7D

Upstream product

• 1146-65-2 naphthalene-d8 
• 90-15-3 α-naphthol 

Downstream Products

• 919514-01-5 d10-methyl-[3-(naphthalen-1-yloxy)-3-thiophen-2-yl-propyl]-amine 
• 362049-56-7 1-naphthyl-d7 N-methylcarbamate 

Relevant articles and documents

Efficient continuous-flow HD exchange reaction of aromatic nuclei in D2O/2-PrOH mixed solvent in a catalyst cartridge packed with platinum on carbon beads

Herein, a continuous-flow deuteration methodology for various aromatic compounds is developed based on heterogeneous platinum-catalyzed hydrogen-deuterium exchange. The reaction entails the transfer of a substrate dissolved in a mixed solvent of 2-propanol and deuterium oxide into a catalyst cartridge packed with platinum on carbon beads (Pt/CB). Pt/ CB could be continuously used without significant deterioration of catalyst activity for at least 24 h. Deuteration proceeded within 60 s of the substrate solutions being passed through the Pt/CB layer in the Pt/CB-packed cartridge.

Efficient and selective Pt/C-catalyzed H-D exchange reaction of aromatic rings

An effective and applicable deuteration method for aromatic rings using Pt/C-D2O-H2 system was established. Especially, phenol was fully deuterated even at room temperature, and other electron-rich aromatic nuclei were efficiently deuterated under mild conditions. The scope and limitations of the presence method and its application to the synthesis of deuterium-labeled biologically active compounds and deuterium-labeled building blocks for practical multi-gram scale syntheses are reported. 2008 The Chemical Society of Japan.

Uranyl-Sensitized Photochemical Oxidation of Naphthalene by Molecular Oxygen. Role of Electron Transfer

Naphthalene quenches the excited state *UO2(2+) in two parallel pathways: oxidation to naphthalene radical cation, C10H8(.+) (Φ = 0.3), and exciplex formation.The overall rate constant in aqueous acetonitrile containing 0.1 M H3PO4 has a value kq = 2.20E9 M-1 s-1.In the presence of O2, a portion of c10H8(.+) is converted to 2-formylcinnamaldehyde and several other products, the rest reacting with UO2(1+) by back electron transfer.