124421-34-7Relevant articles and documents
Amino acid derivative anticonvulsant
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, (2008/06/13)
The present invention relates to compounds of the formula STR1
Preparation and Anticonvulsant Activity of a Series of Functionalized α-Aromatic and α-Heteroaromatic Amino Acids
Kohn, Harold,Sawhney, Kailash N.,LeGall, Philippe,Conley, Judith D.,Robertson, David W.,Leander, J. David
, p. 919 - 926 (2007/10/02)
We recently reported the potent anticonvulsant activity of (R,S)-α-acetamido-N-benzyl-α-phenylacetamide (2b).Selectively substituted derivatives of this compound have now been prepared (23 examples) and evaluated in the maximal electroshock seizure (MES)