1245646-44-9 Usage
Description
7H-Pyrimido[4,5-d]azepine-7-carboxylic acid, 2-amino-3,4,5,6,8,9-hexahydro-4-oxo-, 1,1-dimethylethyl ester is a complex organic chemical compound characterized by a pyrimidoazepine ring system. It features a carboxylic acid group esterified with a 1,1-dimethylethyl (tert-butyl) group, an amino group, and a carbonyl group within its hexahydro structure. 7H-Pyrimido[4,5-d]azepine-7-carboxylic acid, 2-amino-3,4,5,6,8,9-hexahydro-4-oxo-, 1,1-dimethylethyl ester's unique molecular architecture suggests potential reactivity and applications in various fields, particularly in medicinal chemistry and drug development.
Uses
Used in Medicinal Chemistry:
7H-Pyrimido[4,5-d]azepine-7-carboxylic acid, 2-amino-3,4,5,6,8,9-hexahydro-4-oxo-, 1,1-dimethylethyl ester is used as a building block or intermediate in the synthesis of pharmaceutical compounds for its potential to interact with biological targets due to the presence of functional groups like the amino and carbonyl moieties.
Used in Drug Development:
In the pharmaceutical industry, this compound may serve as a precursor or a key component in the development of new drugs, leveraging its structural features to design molecules with specific biological activities, such as binding affinity to receptors or enzymes.
Used in Chemical Research:
7H-Pyrimido[4,5-d]azepine-7-carboxylic acid, 2-amino-3,4,5,6,8,9-hexahydro-4-oxo-, 1,1-dimethylethyl ester is utilized in academic and industrial research settings to explore its chemical properties, reactivity, and potential to form new compounds with desired characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 1245646-44-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,5,6,4 and 6 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1245646-44:
(9*1)+(8*2)+(7*4)+(6*5)+(5*6)+(4*4)+(3*6)+(2*4)+(1*4)=159
159 % 10 = 9
So 1245646-44-9 is a valid CAS Registry Number.
1245646-44-9Relevant articles and documents
Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrimido-[4,5-d]azepines as novel TRPV1 antagonists
Hawryluk, Natalie A.,Merit, Jeffrey E.,Lebsack, Alec D.,Branstetter, Bryan J.,Hack, Michael D.,Swanson, Nadia,Ao, Hong,Maher, Michael P.,Bhattacharya, Anindya,Wang, Qi,Freedman, Jamie M.,Scott, Brian P.,Wickenden, Alan D.,Chaplan, Sandra R.,Breitenbucher, J. Guy
scheme or table, p. 7137 - 7141 (2010/12/25)
Utilization of a tetrahydro-pyrimdoazepine core as a bioisosteric replacement for a piperazine-urea resulted in the discovery a novel series of potent antagonists of TRPV1. The tetrahydro-pyrimdoazepines have been identified as having good in vitro and in
