1245784-81-9Relevant articles and documents
First, second, and third generation scalable syntheses of two potent H 3 antagonists
Pippel, Daniel J.,Mills, John E.,Pandit, Chennagiri R.,Young, Lana K.,Zhong, Hua M.,Villani, Frank J.,Mani, Neelakandha S.
, p. 638 - 648 (2011/12/15)
Our teams have recently completed scale-up campaigns for two structurally similar H3 receptor antagonists. The first and second generation processes were developed for the synthesis of 107 and 125 g batches of (4-cyclobutyl-1,4-diazepan-1-yl)(6
