124594-30-5

Basic information

• Product Name: 2-phenyl-4-(4-chloro-6-methyl-2-pyrimidinylamino)methylene-5(4H)-oxazolone
• Synonyms: 2-phenyl-4-(4-chloro-6-methyl-2-pyrimidinylamino)methylene-5(4H)-oxazolone
• CAS NO: 124594-30-5
• Molecular Weight: 314.731
• Mol File: 124594-30-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-phenyl-4-(4-chloro-6-methyl-2-pyrimidinylamino)methylene-5(4H)-oxazolone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-4-(4-chloro-6-methyl-2-pyrimidinylamino)methylene-5(4H)-oxazolone(124594-30-5)
• EPA Substance Registry System: 2-phenyl-4-(4-chloro-6-methyl-2-pyrimidinylamino)methylene-5(4H)-oxazolone(124594-30-5)

Safety Data

• Hazardous Substances Data: 124594-30-5(Hazardous Substances Data)

Upstream product

• 5600-21-5 2-amino-6-methyl-4-chloropyrimidine 
• 495-69-2 Hippuric Acid 
• 113001-56-2 4-chloro-2-(N,N-dimethylaminomethyleneamino)-6-methylpyrimidine 

Downstream Products

• 124232-32-2 2-phenyl-4-methylene-5(4H)-oxazolone 
• 65-85-0 benzoic acid 
• 124212-06-2 N,N-diethyl(Z)-2-benzoylamino-3-(4-chloro-6-methyl-2-pyrimidinyl)aminopropenamide 
• 124212-10-8 (Z)-2-benzoylamino-3-(4-chloro-6-methyl-2-pyrimidinyl)aminopropenoylhydrazide 
• 124232-35-5 (Z)-2-benzoylamino-3-(4-chloro-6-methyl-2-pyrimidinyl)aminopropenamide 

Relevant articles and documents

The transformations of 4-heteroarylaminomethylene-5(4H)-oxazolones into dehydropeptide derivatives

2-Phenyl-4-heteroarylaminomethylene-5(4H)-oxazolones 3, which were prepared from the corresponding N,N-dimethyl-N'-heteroarylformamidines 1 and hippuric acid 2 in acetic anhydride, react with amino acids giving dehydropeptide derivatives 4, 5, and 6 as products. Dehydration of N-protected peptides 7-10, containing glycine at the C-terminal, followed by the reaction with formamidines 1 gave 2-substituted-4-heteroarylaminomethylene-5(4H)-oxazolones 11-14.