124658-40-8

Basic information

• Product Name: 2-(Dimethoxy-phosphoryl)-4-oxo-4-phenyl-butyric acid
• Synonyms: 2-(Dimethoxy-phosphoryl)-4-oxo-4-phenyl-butyric acid
• CAS NO: 124658-40-8
• Molecular Weight: 286.221
• Mol File: 124658-40-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(Dimethoxy-phosphoryl)-4-oxo-4-phenyl-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Dimethoxy-phosphoryl)-4-oxo-4-phenyl-butyric acid(124658-40-8)
• EPA Substance Registry System: 2-(Dimethoxy-phosphoryl)-4-oxo-4-phenyl-butyric acid(124658-40-8)

Safety Data

• Hazardous Substances Data: 124658-40-8(Hazardous Substances Data)

Upstream product

• 63104-90-5 α-bromo-β-benzoylpropionic acid 
• 121-45-9 phosphorous acid trimethyl ester 
• 96-36-6 methyl phosphite 
• 17812-07-6 Benzoylacrylic acid 

Downstream Products

• 17812-07-6 Benzoylacrylic acid 
• 14274-07-8 methyl trans-β-benzoylacrylate 
• 15121-89-8 ethyl (E)-4-oxo-4-phenyl-2-butenoate 
• 39477-38-8 4-oxo-4-phenyl-2-phenylsulfanyl-butyric acid 

Relevant articles and documents

ORGANOPHOSPHORUS CHEMISTRY 10. THE BEHAVIOUR OF β-AROYLACRYLIC ACIDS TOWARD NUCLEOPHILIC PHOSPHORUS COMPOUNDS

The reaction of alkyl phosphites and thiolphosphoric acids with β-aroylacrylic acids 1a,b has been investigated.Dialkyl phosphites (DAP) attacked 1 at the β-carbon atom with respect to the aroyl-carbonyl function, to give phosphonate 1:1 adducts assigned structure 2A.Thiolphosphoric acids (7) attacked 1 at the same centre to give adducts 8.On the other hand, trialkyl phosphites (TAP) converted 1 into the respective esters 5, almost exclusively.Structures of the new products were assigned according to consistent analytical and spectroscopic measurements.Key words: β-aroylacrylic acids; alkylation; phosphorylation; thiophosphorylation.