1246811-62-0Relevant articles and documents
Concise synthesis of 5,6-dihydrovaltrate leading to enhanced Rev-export inhibitory congener
Tamura, Satoru,Fujiwara, Katsuaki,Shimizu, Nobuhiro,Todo, Shingo,Murakami, Nobutoshi
, p. 5975 - 5980 (2010)
The concise synthesis of 5,6-dihydrovaltrate (2), the bioisostere of valtrate (1) showing anti-HIV activity by inhibition for nuclear export of Rev, has been achieved from the commercially available iridoid genipin (3). Analysis of steric influence of the