1246965-74-1

Basic information

• Product Name: 1-bromo-4-chloro-2-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)benzene
• Synonyms: 1-bromo-4-chloro-2-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)benzene
• CAS NO: 1246965-74-1
• Molecular Weight: 319.936
• Mol File: 1246965-74-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-bromo-4-chloro-2-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-4-chloro-2-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)benzene(1246965-74-1)
• EPA Substance Registry System: 1-bromo-4-chloro-2-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)benzene(1246965-74-1)

Safety Data

• Hazardous Substances Data: 1246965-74-1(Hazardous Substances Data)

Upstream product

• 174265-12-4 2-bromo-5-chlorobenzaldehyde 
• 354-58-5 1,1,1-Trichloro-2,2,2-trifluoroethane 

Downstream Products

• 1448458-61-4 7-chloro-2-phenyl-4-(trifluoromethyl)benzo[b]oxepine 

Relevant articles and documents

Copper-catalyzed thiolation annulations of 1,4-dihalides with sulfides leading to 2-trifluoromethyl benzothiophenes and benzothiazoles

Copper-catalyzed double thiolation reaction of 1,4-dihalides with sulfides has been developed for selectively synthesizing 2-trifluoromethyl benzothiophenes and benzothiazoles. In the presence of CuI, a variety of 2-halo-1-(2-haloaryl)-3,3,3-trifluoropropylenes smoothly underwent the thiolation annulation with Na2S to afford 2-trifluoromethyl benzothiophenes in moderate to good yields. Moreover, the conditions are compatible with N-(2-haloaryl)trifluoroacetimidoyl chlorides in the presence of NaHS and K3PO4, leading to 2-trifluoromethyl benzothiazoles.