124854-94-0

Basic information

• Product Name: (E)-3-(2-bromophenyl)prop-2-en-1-ol
• Synonyms: (E)-3-(2-bromophenyl)prop-2-en-1-ol
• CAS NO: 124854-94-0
• Molecular Formula: C₉H₉BrO
• Molecular Weight: 213.07116
• Mol File: 124854-94-0.mol
• Article Data: 34

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-3-(2-bromophenyl)prop-2-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(2-bromophenyl)prop-2-en-1-ol(124854-94-0)
• EPA Substance Registry System: (E)-3-(2-bromophenyl)prop-2-en-1-ol(124854-94-0)

Safety Data

• Hazardous Substances Data: 124854-94-0(Hazardous Substances Data)

Upstream product

• 102540-15-8 methyl (2E)-3-(2-bromophenyl)-2-propenoate 
• 114837-50-2 2-bromo-α-(ethenyl)benzenemethanol 
• 23147-58-2 glycolaldehyde dimer 
• 6630-33-7 ortho-bromobenzaldehyde 
• 102540-15-8 3-(2-bromophenyl)-acrylic acid methyl ester 
• 99134-25-5 (E:Z)-3-(2-bromo-phenyl)-acrylic acid ethyl ester 
• 91047-77-7 ethyl (2E)-3-(2-bromophenyl)prop-2-enoate 
• 116509-98-9 2-bromo-1-(3-hydroxyprop-1-yn-1-yl)benzene 
• 583-55-1 1-Bromo-2-iodobenzene 
• 66223-53-8 trans-2-bromocinnamaldehyde 
• 7345-79-1 2-bromocinnamic acid 
• 7345-79-1 2-bromocinnamic acid 

Downstream Products

• 66223-53-8 trans-2-bromocinnamaldehyde 
• 1613157-23-5 (E)-4-(2-bromophenyl)but-3-enoic acid 
• 1578259-52-5 (E)-3-(2-bromophenyl)allyl acetate 
• 124854-95-1 (E)-1-bromo-2-(3-bromoprop-1-en-1-yl)benzene 
• 90725-35-2 1-bromo-2-(3-chloro-propenyl)benzene 

Relevant articles and documents

Synthesis of Enantioenriched 3,4-Disubstituted Chromans through Lewis Base Catalyzed Carbosulfenylation

A method for the catalytic, enantioselective, carbosulfenylation of alkenes to construct 3,4-disubstituted chromans is described. Alkene activation proceeds through the intermediacy of enantioenriched, configurationally stable thiiranium ions generated from catalytic, Lewis base activation of an electrophilic sulfenylating agent. The transformation affords difficult-to-generate, enantioenriched, 3,4-disubstituted chromans in moderate to high yields and excellent enantioselectivities. A variety of substituents are compatible including electronically diverse functional groups as well as several functional handles such as aryl halides, esters, anilines, and phenols. The resulting thioether moiety is amenable to a number of functional group manipulations and transformations. Notably, the pendant sulfide was successfully cleaved to furnish a free thiol which readily provides access to most sulfur-containing functional groups which are present in natural products and pharmaceuticals.

Wittig Olefination Using Phosphonium Ion-Pair Reagents Incorporating an Endogenous Base

Despite common perception, the use of strong bases in Wittig chemistry is utterly unnecessary: we report a series of novel ion-pair phosphonium carboxylate reagents which are essentially "storable ylides". These reagents are straightforwardly prepared in excellent yields, and their fluxional nature permits clean olefination of a broad range of aldehydes and even hemiacetals.

Selective Synthesis of Z-Cinnamyl Ethers and Cinnamyl Alcohols through Visible Light-Promoted Photocatalytic E to Z Isomerization

A photocatalytic E to Z isomerization of alkenes using an iridium photosensitizer under mild reaction conditions is disclosed. This method provides scalable and efficient access to Z-cinnamyl ether and allylic alcohol derivatives in high yields with excellent stereoselectivity. Importantly, this method also provides a powerful strategy for the selective synthesis of Z-magnolol and honokiol derivatives possessing potential biological activity.