1249-67-8 Usage
Description
17-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate, also known as hydrocortisone acetate, is a synthetic steroid hormone derivative belonging to the class of corticosteroids. It possesses anti-inflammatory, immunosuppressive, and anti-allergic properties, making it a valuable pharmaceutical ingredient in various medications.
Uses
Used in Pharmaceutical Industry:
17-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate is used as an active pharmaceutical ingredient for the treatment of conditions such as eczema, dermatitis, and allergic reactions. It is effective in reducing inflammation and suppressing the immune response, providing relief to affected individuals.
Used in Topical Medications:
In the form of creams, ointments, and topical solutions, 17-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate is used as a local treatment applied directly to the affected area of the skin. This allows for targeted relief and minimizes systemic side effects associated with oral corticosteroids.
Check Digit Verification of cas no
The CAS Registry Mumber 1249-67-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,4 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1249-67:
(6*1)+(5*2)+(4*4)+(3*9)+(2*6)+(1*7)=78
78 % 10 = 8
So 1249-67-8 is a valid CAS Registry Number.
1249-67-8Relevant articles and documents
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Rosenkranz et al.
, p. 4081,4084 (1950)
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Synthesis of the corticoid side chain from 17α-(haloethynyl)-17β-(nitrooxy)androstenes
Hofmeister,Annen,Laurent,Wiechert
, p. 423 - 426 (2007/10/02)
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Process for the preparation of 17-haloethynyl steroids, and novel 17-haloethynyl steroids
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, (2008/06/13)
17-haloethynyl steroids of the partial formula STR1 wherein R1 is hydrogen or methyl, R2 is alkyl of 1-4 carbon atoms, acyl of 1-7 carbon atoms, trimethylsilyl, 2-tetrahydropyranyl, or nitrate, X is bromine or iodine, and V is methyl
