124988-64-3

Basic information

• Product Name: (S)-4-phenyl-1,2-butanediol
• Synonyms: (S)-4-phenyl-1,2-butanediol
• CAS NO: 124988-64-3
• Molecular Weight: 166.22
• Mol File: 124988-64-3.mol
• Article Data: 63

Chemical Properties

• CAS DataBase Reference: (S)-4-phenyl-1,2-butanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-phenyl-1,2-butanediol(124988-64-3)
• EPA Substance Registry System: (S)-4-phenyl-1,2-butanediol(124988-64-3)

Safety Data

• Hazardous Substances Data: 124988-64-3(Hazardous Substances Data)

Upstream product

• 80735-94-0 1-Phenyl-3-buten-1-ol 
• 768-56-9 4-Phenylbut-1-ene 
• 85531-71-1 (3-benzyloxiran-2-yl)methanol 
• 92527-69-0 1-Benzyloxy-4-phenylbutan-2-ol 
• 134916-70-4 4-phenylbutane-1,2-diyl diacetate 
• 78571-81-0 (3-benzyloxiran-2-yl)methanol 
• 16939-57-4 (E)-buta-1,3-dienylbenzene 
• 104-53-0 3-phenyl-propionaldehyde 
• 50-00-0 formaldehyd 
• 19344-91-3 (2,3-diphenyl-isoxazolidin-5-yl)-methanol 
• 20296-07-5 1-hydroxy-4-phenyl-2-butanone 
• 125639-64-7 (S)-ethyl 2-hydroxy-4-phenylbutyrate 
• 115016-95-0 (S)-2-hydroxy-4-phenylbutanoic acid 
• 146912-63-2 (S)-2-hydroxy-4-oxo-4-phenylbutanoic acid 

Downstream Products

• 173917-44-7 1-(tert-butyl-dimethylsilyloxy)-4-phenylbutan-2-ol 
• 143216-63-1 (2R,4R)-4-Amino-4-phenyl-butane-1,2-diol 
• 212560-65-1 (R)-tert-butyl (3-oxo-1-phenylpropyl)carbamate 
• 620989-96-0 (2R,4S)-4-Amino-4-phenyl-butane-1,2-diol 
• 1567840-67-8 2,2-di-tert-butyl-4-phenethyl-1,3,2-dioxasilolane 
• 710-11-2 2-oxo-4-phenylbutyric acid 
• 4263-93-8 2-hydroxy-4-phenylbutanoic acid 
• 1430731-60-4 (S)-(+)-2-(tert-butyldimethylsilyloxy)-4-phenylbutyl pivalate 

Relevant articles and documents

Enantioselective reduction of α-keto esters to 1,2-diols using the NaBH4/Me3SiCl system catalyzed by polymer-supported chiral sulfonamide

In the presence of 25mol% of a polymer-supported chiral sulfonamide, a variety of α-keto esters can be reduced into the corresponding 1,2-diols in good yields and high enantioselectivities using the NaBH4/Me 3SiCl reducing system.

Lewis Base Catalyzed Dioxygenation of Olefins with Hypervalent Iodine Reagents

1,2-Diols are extremely useful building blocks in organic synthesis. Hypervalent iodine reagents are useful for the vicinal dihydroxylation of olefins to give 1,2-diols under metal-free conditions, but strongly acidic promoters are often required. Herein, we report a catalytic vicinal dioxygenation of olefins with hypervalent iodine reagents using Lewis bases as catalysts. The conditions are mild and compatible with various functional groups.

Iron-Catalyzed Diborylation of Unactivated Aliphatic gem-Dihalogenoalkenes: Synthesis of 1,2-Bis(boryl)alkanes

Herein, we report the first example of iron-catalyzed defluoroborylation of unactivated gem-difluoroalkenes, gem-dichloroalkenes, and gem-dibromoalkenes, providing the 1,2-bis(boryl)alkanes in moderate to good yield. This transformation has high regiosele

Site-Selective Mono-Oxidation of 1,2-Bis(boronates)

Site-selective oxidation of vicinal bis(boronates) is accomplished through the use of trimethylamine N-oxide in 1-butanol solvent. The reaction occurs with good efficiency and selectivity across a range of substrates, providing 2-hydro-1-boronic esters which are shown to be versatile intermediates in the synthesis of chiral building blocks.