125016-15-1 Usage
Description
3,4-Dichloro-4'-Methylbenzophenone, also known as DCM, is a chemical compound with the molecular formula C14H10Cl2O. It is a white to light yellow crystalline solid that is primarily used as a photoinitiator in UV-curable coatings, inks, and adhesives. DCM is also used as a stabilizer for polymers and as a UV blocker in various industrial applications. It is considered to be a potential skin and eye irritant and may have harmful effects if inhaled or ingested. Additionally, DCM has been found to have potential environmental impacts and has been subject to regulatory scrutiny in some regions.
Uses
Used in Coatings Industry:
3,4-Dichloro-4'-Methylbenzophenone is used as a photoinitiator for UV-curable coatings, enabling rapid curing and providing excellent adhesion, durability, and resistance to chemicals and abrasion.
Used in Inks Industry:
In the inks industry, 3,4-Dichloro-4'-Methylbenzophenone is used as a photoinitiator for UV-curable inks, offering fast drying times, high resolution, and resistance to fading and wear.
Used in Adhesives Industry:
3,4-Dichloro-4'-Methylbenzophenone is used as a photoinitiator for UV-curable adhesives, providing strong bonding, rapid curing, and resistance to environmental factors.
Used in Polymer Stabilization:
3,4-Dichloro-4'-Methylbenzophenone is used as a stabilizer for polymers, preventing degradation and discoloration caused by exposure to UV light and heat, thereby extending the lifespan and maintaining the properties of the polymers.
Used in UV Protection:
In various industrial applications, 3,4-Dichloro-4'-Methylbenzophenone is used as a UV blocker to protect materials from the harmful effects of ultraviolet radiation, such as degradation, discoloration, and loss of mechanical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 125016-15-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,0,1 and 6 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 125016-15:
(8*1)+(7*2)+(6*5)+(5*0)+(4*1)+(3*6)+(2*1)+(1*5)=81
81 % 10 = 1
So 125016-15-1 is a valid CAS Registry Number.
InChI:InChI=1/C14H10Cl2O/c1-9-2-4-10(5-3-9)14(17)11-6-7-12(15)13(16)8-11/h2-8H,1H3
125016-15-1Relevant articles and documents
Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain
Fujii, Naoaki,Mallari, Jeremy P.,Hansell, Elizabeth J.,MacKey,Doyle, Patricia,Zhou,Gut, Jiri,Rosenthal, Philip J.,McKerrow, James H.,Guy, R. Kiplin
, p. 121 - 123 (2007/10/03)
Herein we report the synthesis and evaluation of a series of thiosemicarbazones as potential inhibitors of cysteine proteases relevant to parasitic diseases. Derivatives of thiosemicarbazone 1 were discovered to be potent inhibitors of cruzain and rhodesain, crucial proteases in the life cycles of Trypanosoma cruzi and T. brucei rhodesiense, the organisms causing Chagas' disease and sleeping sickness. However, the entire series had only modest potency against falcipain-2, an essential protease for Plasmodium falciparum, the organism causing malaria. Among the active inhibitors, several potently inhibited proliferation of cultures of T. brucei. However, only modest activity was observed in inhibition of proliferation of T. cruzi or P. falciparum. Herein we report the synthesis and evaluation of a series of thiosemicarbazones as potential inhibitors of cysteine proteases relevant to parasitic diseases. Derivatives of thiosemicarbazone 1 were discovered to be potent inhibitors of cruzain and rhodesain, crucial proteases in the life cycles of Trypanosoma cruzi and T. brucei rhodesiense, the organisms causing Chagas' disease and sleeping sickness. However, the entire series had only modest potency against falcipain-2, an essential protease for Plasmodium falciparum, the organism causing malaria. Among the active inhibitors, several potently inhibited proliferation of cultures of T. brucei. However, only modest activity was observed in inhibition of proliferation of T. cruzi or P. falciparum.