1251931-78-8Relevant articles and documents
Initial Scale-Up and Process Improvements for the Preparation of a Lead Antibacterial Macrolone Compound
Stimac, Vlado,Matanovic Skugor, Maja,Palej Jakopovic, Ivana,Vinter, Adrijana,Ilijas, Marina,Alihodzc, Sulejman,Mutak, Stjepan
, p. 1393 - 1401 (2011/09/20)
Macrolones are a novel class of potent antimicrobial agents that consist of a macrolide scaffold to which a quinolone unit is tethered by various linkers to the 4 -O-position of the cladinose sugar. In this paper is described a modified 13-step route to a