125217-79-0

Basic information

• Product Name: N-methyl-6β-(phenylsulphonyl)-8-azabicyclo<3.2.1>oct-3-en-2-one
• CAS NO: 125217-79-0
• Molecular Weight: 277.344
• Mol File: 125217-79-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-methyl-6β-(phenylsulphonyl)-8-azabicyclo<3.2.1>oct-3-en-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-6β-(phenylsulphonyl)-8-azabicyclo<3.2.1>oct-3-en-2-one(125217-79-0)
• EPA Substance Registry System: N-methyl-6β-(phenylsulphonyl)-8-azabicyclo<3.2.1>oct-3-en-2-one(125217-79-0)

Safety Data

• Hazardous Substances Data: 125217-79-0(Hazardous Substances Data)

Upstream product

• 25065-00-3 1-methyl-pyridinium-3-olate 
• 5535-48-8 PVS 
• 100-39-0 benzyl bromide 
• 109-00-2 3-HYDROXYPYRIDINE 
• 7500-05-2 3-hydroxy-1-methylpyridin-1-ium iodide 

Downstream Products

• 13466-55-2 tropan-2β-ol 
• 64530-37-6 Acetic acid (1R,2S,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl ester 
• 64530-37-6 Acetic acid (1R,2R,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl ester 
• 13466-55-2 tropan-2α-ol 
• 125217-81-4 (1S,2R,5S,6R)-6-Benzenesulfonyl-8-methyl-8-aza-bicyclo[3.2.1]octan-2-ol 
• 125217-81-4 (1S,2S,5S,6R)-6-Benzenesulfonyl-8-methyl-8-aza-bicyclo[3.2.1]octan-2-ol 

Relevant articles and documents

A facile and efficient synthesis of (±)-tropan-2-one

The facile and efficient multigram synthesis of (±)-tropan-2-one 1 was achieved in six steps (65% overall yield) from N-methyl-3-oxopyridyl hydroiodide 3.

ASYMMETRIC 1,3-DIPOLAR CYCLOADDITION OF CHIRAL SULPHINYLETHENES WITH 1-METHYL-3-OXIDOPYRIDINIUM AND SOME NITRONES

1,3-Dipolar cycloaddition of (R)-(+)-p-tolyl vinyl sulphoxide 1 with 1-methyl-3-oxidopyridinium 6 proceeded in a diastereoselective manner to afford the exo and endo cycloadducts 11a,b and 12a in 36percent, 7percent and 29percent yield, respectively.The a

1,3-Dipolar Cycloaddition of 1-Methyl-3-oxidopyridinium and Sulfonylethenes. A Synthesis of 2-Tropanols and Monofluorinated 2-Tropanol

2α- and 2β-Tropanols were synthesized by 1,3-dipolar cycloaddition of phenyl vinyl sulfone and 1-methyl-3-oxidopyridinium regio- and stereoselectively.The method was extended to a preparation of 6α-fluoro-2β-tropanol from 1-(benzenesulfonyl)-1-fluoroethene.