1252831-04-1Relevant articles and documents
Regioselective palladium-catalyzed arylation of 4-chloropyrazoles
Mateos, Carlos,Mendiola, Javier,Carpintero, Mercedes,Minguez, Jose Miguel
scheme or table, p. 4924 - 4927 (2011/02/21)
A highly regioselective Pd-catalyzed arylation of N-methylpyrazoles with aryl bromides is described. This transformation was studied extensively via automated reaction screening. A Design of Experiments (DoE) approach for optimizing the critical parameter