1253-43-6

Basic information

• Product Name: cortisol 21-sulfate
• Synonyms: cortisol 21-sulfate;(11β)-11,17-Dihydroxy-21-(sulfooxy)pregn-4-ene-3,20-dione;11β,17-Dihydroxy-3,20-diketopregn-4-ene-21-yl Sulfate;11β,17α-Dihydroxy-3,20-diketopregn-4-ene-21-yl Sulfate;11β,17α-Dihydroxypregn-4-ene-3,20;Cortisol 21-(Hydrogen Sulfate);Hydrocortisone 21-sulfate potassium salt
• CAS NO: 1253-43-6
• Molecular Formula: C₂₁H₃₀O₈S
• Molecular Weight: 442.52
• Product Categories: Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Steroids;Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
• Mol File: 1253-43-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.44g/cm³
• Refractive Index: 1.609
• CAS DataBase Reference: cortisol 21-sulfate(CAS DataBase Reference)
• NIST Chemistry Reference: cortisol 21-sulfate(1253-43-6)
• EPA Substance Registry System: cortisol 21-sulfate(1253-43-6)

Safety Data

• Hazardous Substances Data: 1253-43-6(Hazardous Substances Data)

Usage

Description

Cortisol 21-sulfate, also known as a steroid sulfate, is a phase II metabolite of cortisol, which is formed by the formal condensation of the hydroxy group at position 21 of cortisol with sulfuric acid. cortisol 21-sulfate plays a significant role in various biological processes and has potential applications in different industries.

Uses

Used in Pharmaceutical Industry:
Cortisol 21-sulfate is used as a diagnostic marker for monitoring cortisol levels in the body. It is particularly useful in the detection and management of adrenal disorders, as well as in assessing the body's response to stress.
Used in Research and Development:
Cortisol 21-sulfate serves as an essential compound in scientific research, particularly in the study of steroid metabolism and the role of cortisol in various physiological processes. It can be used to develop new drugs and therapies targeting cortisol-related conditions.
Used in Clinical Laboratories:
Cortisol 21-sulfate is utilized as a reference material in clinical laboratories for the accurate measurement of cortisol levels in blood samples. This helps in the diagnosis and treatment of various health conditions related to cortisol imbalance.
Used in Sports Medicine:
Cortisol 21-sulfate can be employed as a biomarker to monitor the effects of physical stress and exercise on the body. It can help athletes and sports professionals to optimize their training regimens and improve their performance by understanding the impact of stress on their cortisol levels.

InChI:InChI=1/C21H30O8S/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19/h9,14-16,18,23,25H,3-8,10-11H2,1-2H3,(H,26,27,28)/t14-,15-,16-,18+,19-,20-,21-/m0/s1

Upstream product

• 50-23-7 HYDROCORTISONE 

Relevant articles and documents

Steroid conjugates IV. The preparation of steroid sulfates with triethylamine-sulfur trioxide.

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