1253091-76-7

Basic information

• Product Name: methyl 2-((tert-butoxycarbonyl)amino)-2-(2-chlorophenyl)acetate
• Synonyms: methyl 2-((tert-butoxycarbonyl)amino)-2-(2-chlorophenyl)acetate
• CAS NO: 1253091-76-7
• Molecular Weight: 299.754
• Mol File: 1253091-76-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-((tert-butoxycarbonyl)amino)-2-(2-chlorophenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-((tert-butoxycarbonyl)amino)-2-(2-chlorophenyl)acetate(1253091-76-7)
• EPA Substance Registry System: methyl 2-((tert-butoxycarbonyl)amino)-2-(2-chlorophenyl)acetate(1253091-76-7)

Safety Data

• Hazardous Substances Data: 1253091-76-7(Hazardous Substances Data)

Upstream product

• 141109-17-3 (+/-)-2-chlorophenylglycine methyl ester hydrochloride 
• 67-56-1 methanol 
• 313490-25-4 [(tert-butoxycarbonyl)amino](2-chlorophenyl)acetic acid 

Downstream Products

• 141109-14-0 methyl (S)-(+)-2-amino-2-(2-chlorophenyl)acetate 
• 141109-16-2 α-amino-(2-chlorophenyl)acetic acid methyl ester 
• 1001414-68-1 (R)-(-)-methyl 2-(tert-butoxycarbonylamino)-2-(2-chlorophenyl)acetate 
• 1212602-23-7 (2R)-[(tert-butoxycarbonyl)amino](2-chlorophenyl)ethanoic acid 
• 225918-60-5 N-Boc-(S)-2-chlorophenylglycine 
• 86169-24-6 (R)-(2-chlorophenyl)glycine 
• 141315-50-6 (S)-2-amino-(2-chlorophenyl)ethanoic acid 

Relevant articles and documents

Tert-Butyl(3-cyano-4,6-dimethylpyridin-2-yl)carbonate as a green and chemoselective N-tert-butoxycarbonylation reagent

The use of tert-butyl(3-cyano-4,6-dimethylpyridin-2-yl)carbonate as a chemoselective tert-butoxycarbonylation reagent for aromatic and aliphatic amines has been demonstrated. To gain insight into this reaction, in situ React IR technology was used to confirm the effectivity and chemoselectivity of this novel Boc reagent. The reaction was carried out chemoselectively in high yield under mild, environment-friendly conditions and was completed quickly within 1 hour. Simultaneously, the Boc carrier was easily recyclable, and has great application prospects for industrial production.