1253768-91-0 Usage
Description
(Z)-3-(hydroxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid is a chemical compound derived from the indole family, characterized by its heterocyclic structure and the presence of hydroxy and carboxylic acid functional groups. These groups may endow the compound with various biological activities, making it a potential candidate for therapeutic applications in the field of medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
(Z)-3-(hydroxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid is used as a potential therapeutic agent for its possible antioxidant, anti-inflammatory, or antimicrobial properties. (Z)-3-(hydroxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid's structure suggests that it may be effective in treating a range of conditions, making it a promising candidate for further research and development.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (Z)-3-(hydroxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid is used as a subject of study for its potential pharmacological properties. (Z)-3-(hydroxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid's hydroxy and carboxylic acid groups may allow it to interact with biological targets, providing insights into its possible applications in drug discovery and development.
Used in Drug Delivery Systems:
Similar to gallotannin, (Z)-3-(hydroxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid could be employed in novel drug delivery systems to enhance its applications and efficacy. The development of organic and metallic nanoparticles as carriers for this compound could improve its delivery, bioavailability, and therapeutic outcomes, particularly if it demonstrates potent biological activities in further research.
Check Digit Verification of cas no
The CAS Registry Mumber 1253768-91-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,3,7,6 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1253768-91:
(9*1)+(8*2)+(7*5)+(6*3)+(5*7)+(4*6)+(3*8)+(2*9)+(1*1)=180
180 % 10 = 0
So 1253768-91-0 is a valid CAS Registry Number.
1253768-91-0Relevant articles and documents
ALK5 INHIBITOR CONJUGATES AND USES THEREOF
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Paragraph 0191; 0197-0198, (2021/07/17)
The present disclosure relates to targeted drug conjugates comprising ALK5 inhibitors and targeting moieties that direct the ALK5 inhibitors to cells involved in fibrosis and cancer, for example myofibroblasts, activated fibroblasts and transitioning fibr
ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES
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Paragraph 0199; 0205-0206, (2020/06/07)
The present disclosure relates to antibody-drug conjugates comprising ALK5 inhibitors and their uses.
Design, synthesis, and evaluation of indolinones as inhibitors of the transforming growth factor β receptor i (TGFβRI)
Roth, Gerald J.,Heckel, Armin,Brandl, Trixi,Grauert, Matthias,Hoerer, Stefan,Kley, Joerg T.,Schnapp, Gisela,Baum, Patrick,Mennerich, Detlev,Schnapp, Andreas,Park, John E.
supporting information; experimental part, p. 7287 - 7295 (2011/02/23)
Inhibition of transforming growth factor β (TGFβ) type I receptor (Alk5) offers a novel approach for the treatment of fibrotic diseases and cancer. Indolinones substituted in position 6 were identified as a new chemotype inhibiting TGFβRI concomitant with
