125455-64-3 Usage
Description
4-NITROPHENYL 2-ACETAMIDO-3-O-(2-ACETAMIDO-2-DEOXY-B-D-GLUCOPYRANOSYL)-2-DEOXY-A-D-GALACTOPYRANOSIDE is a complex organic compound, specifically a glycoconjugate, characterized by its white crystalline solid appearance. It is an analogue of p-nitrophenyl T-antigen, which is a significant molecule in the study of certain enzymes and their substrate specificity.
Uses
Used in Biochemical Research:
4-NITROPHENYL 2-ACETAMIDO-3-O-(2-ACETAMIDO-2-DEOXY-B-D-GLUCOPYRANOSYL)-2-DEOXY-A-D-GALACTOPYRANOSIDE is used as a potential substrate in biochemical research for elucidating the substrate specificity of endo-α-N-acetylgalactosaminidase, an enzyme involved in the degradation of glycoconjugates.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, this compound serves as a valuable tool for the development of drugs targeting enzymes that interact with glycoconjugates, which may have implications in the treatment of various diseases, including cancer and other conditions related to abnormal glycosylation processes.
Used in Diagnostic Applications:
As an analogue of p-nitrophenyl T-antigen, this compound can also be utilized in the development of diagnostic tools and assays to detect and measure the activity of endo-α-N-acetylgalactosaminidase, which could be relevant in the clinical evaluation of certain disease states or conditions.
Chemical Properties:
The compound is a white crystalline solid, which indicates its stability and suitability for use in various experimental setups and applications. Its chemical structure and properties make it an interesting candidate for further research and development in the fields of biochemistry, pharmaceuticals, and diagnostics.
Check Digit Verification of cas no
The CAS Registry Mumber 125455-64-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,4,5 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 125455-64:
(8*1)+(7*2)+(6*5)+(5*4)+(4*5)+(3*5)+(2*6)+(1*4)=123
123 % 10 = 3
So 125455-64-3 is a valid CAS Registry Number.
InChI:InChI=1/C22H31N3O13/c1-9(28)23-15-19(32)17(30)13(7-26)36-21(15)38-20-16(24-10(2)29)22(37-14(8-27)18(20)31)35-12-5-3-11(4-6-12)25(33)34/h3-6,13-22,26-27,30-32H,7-8H2,1-2H3,(H,23,28)(H,24,29)
125455-64-3Relevant articles and documents
Synthesis of mucin O-glycan core structures as their p-nitro- and p-aminophenyl glycosides
Hollinger, Martin,Abraha, Fana,Oscarson, Stefan
, p. 1454 - 1466 (2011/08/22)
For the investigation of glycosidases, and for the construction of glycan arrays the p-nitrophenyl- and p-aminophenyl glycosides of mucin O-glycan core structures 1-7 and the 2,6-ST-antigen have been chemically synthesized using d-galactose as a precursor for GalNAc residues. GlcNAc residues have partly been introduced using a 4,6-di-O-benzoyl-2,3-N,O-oxazolidinone-protected donor, which allowed deprotection of the formed di- and tri-saccharides in one step using sodium methoxide.
