1254592-72-7

Basic information

• Product Name: C₁₅H₂₅N₃O₄PdS*H₂O
• CAS NO: 1254592-72-7
• Molecular Weight: 467.882
• Mol File: 1254592-72-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₂₅N₃O₄PdS*H₂O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₂₅N₃O₄PdS*H₂O(1254592-72-7)
• EPA Substance Registry System: C₁₅H₂₅N₃O₄PdS*H₂O(1254592-72-7)

Safety Data

• Hazardous Substances Data: 1254592-72-7(Hazardous Substances Data)

Upstream product

• 15020-99-2 Pd(ethylenediamine)Cl₂ 
• 34235-81-9 3-methyl-2-{[(4-methylphenyl)sulfonyl]amino}pentanoic acid 
• 98-59-9 p-toluenesulfonyl chloride 
• 73-32-5 L-isoleucine 

Relevant articles and documents

Synthesis, characterization, and cytotoxicity of platinum(II)/palladium(II) complexes with 4-toluenesulfonyl-L-amino acid dianion and diimine/diamine

Eight new platinum(II)/palladium(II) complexes with 4-toluenesulfonyl-L- amino acid dianion and diimine/diamine ligands, [Pd(en)(Tsile)]·H 2O (1), [Pd(bipy)(Tsile)] (2), [Pd(bipy)(Tsthr)]·0.5H 2O (3), [Pd(phen)(Tsile)]·0.5H2O (4), [Pd(phen)(Tsthr)]·H2O (5), [Pd(bqu)(Tsthr)]·1.5H 2O (6), [Pt(en)(Tsser)] (7), and [Pt(en)(Tsphe)]·H 2O (8), have been synthesized and characterized by elemental analyses, 1H NMR and mass spectrometry. The crystal structure of 7 has been determined by X-ray diffraction. Cytotoxicities were tested by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and sulforhodamine B assays. The complexes exert cytotoxicity against HL-60, Bel-7402, BGC-823, and KB cell lines with 4 having the best cytotoxicity against HL-60, Bel-7402, and BGC-823 cell lines; the compounds are less cytotoxic than cisplatin.