1255529-28-2 Usage
Description
EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2S,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]-, also known as Edoxaban Impurity H, is an impurity of Edoxaban (E555520). Edoxaban is an anticoagulant drug that acts as a direct factor Xa inhibitor. Edoxaban Impurity H is a useful pharmaceutical standard for the development and quality control of Edoxaban.
Uses
Used in Pharmaceutical Industry:
EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2S,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]is used as a pharmaceutical standard for the development and quality control of Edoxaban, an anticoagulant drug that acts as a direct factor Xa inhibitor. Its role as an impurity helps in ensuring the purity and efficacy of the main drug, contributing to the overall safety and effectiveness of the medication.
Check Digit Verification of cas no
The CAS Registry Mumber 1255529-28-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,5,5,2 and 9 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1255529-28:
(9*1)+(8*2)+(7*5)+(6*5)+(5*5)+(4*2)+(3*9)+(2*2)+(1*8)=162
162 % 10 = 2
So 1255529-28-2 is a valid CAS Registry Number.
1255529-28-2Relevant articles and documents
OXAMIDE DERIVATIVE
-
Page/Page column 17, (2012/03/12)
The present invention provides an isomer of N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide represented by formula (II) or a salt thereof, or a solvate thereof. Such an isomer or a salt thereof, or a solvate thereof is useful as a standard in a test for inspecting impurities in a pharmaceutical composition containing a compound represented by formula (II) or a salt thereof, or a hydrate thereof. The present invention also relates to a substantially pure compound that is useful as a preventive and/or therapeutic drug for thrombotic diseases, and a pharmaceutical composition containing the substantially pure compound.