1256382-81-6Relevant articles and documents
4-oxo-1,4-dihydropyridines as selective CB2 cannabinoid receptor ligands: Structural insights into the design of a novel inverse agonist series
El Bakali, Jamal,Muccioli, Giulio G.,Renault, Nicolas,Pradal, Delphine,Body-Malapel, Mathilde,Djouina, Madjid,Hamtiaux, Laurie,Andrzejak, Virginie,Desreumaux, Pierre,Chavatte, Philippe,Lambert, Didier M.,Millet, Régis
, p. 7918 - 7931 (2011/03/19)
Growing evidence shows that CB2 receptor is an attractive therapeutic target. Starting from a series of 4-oxo-1,4-dihydroquinoline-3- carboxamide as selective CB2 agonists, we describe here the medicinal chemistry approach leading to
