1256782-84-9

Basic information

• Product Name: 5-trifluoromethyl-(1-(4-amino)benzyl)pyridine-2(1H)-one
• Synonyms: 5-trifluoromethyl-(1-(4-amino)benzyl)pyridine-2(1H)-one
• CAS NO: 1256782-84-9
• Molecular Weight: 268.238
• Mol File: 1256782-84-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-trifluoromethyl-(1-(4-amino)benzyl)pyridine-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-trifluoromethyl-(1-(4-amino)benzyl)pyridine-2(1H)-one(1256782-84-9)
• EPA Substance Registry System: 5-trifluoromethyl-(1-(4-amino)benzyl)pyridine-2(1H)-one(1256782-84-9)

Safety Data

• Hazardous Substances Data: 1256782-84-9(Hazardous Substances Data)

Upstream product

• 52334-81-3 2-chloro-5-trifluoromethylpyridine 
• 100-14-1 4-nitrobenzyl chloride 
• 1365919-82-9 2-chloro-5-trifluoromethyl-pyridine 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 33252-63-0 5-(trifluoromethyl)-2(1H)-pyridone 
• 923688-20-4 5-trifluoromethyl-(1-(4-nitro)benzyl)pyridine-2(1H)-one 

Downstream Products

• 1256782-95-2 5-trifluoromethyl-(1-(4-acetylamino)benzyl)pyridine-2(1H)-one 
• 1365919-54-5 1-(4-(2-(2-hydroxyethoxy)ethylamino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one 
• 1256782-88-3 1-(4-((2-hydroxyethyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one 
• 1365919-48-7 1-(4-((3-hydroxypropyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one 
• 1256782-86-1 1-(4-(3-piperidin-1-yl)propylaminobenzyl)-5-(trifluoromethyl)pyridin-2(1H)-one 
• 1256782-90-7 1-(4-((2-morpholinoethyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one 
• 1256782-87-2 1-(4-((3-(4-methylpiperazin-1-yl)propyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one 
• 1256783-05-7 1-(4-((2-chloroethyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one 
• 1256782-93-0 1-(4-((2-(4-(2-hydroxyethyl)piperazin-1-yl)ethyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one 
• 1256782-92-9 1-(4-((2-(piperazin-1-yl)ethyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one 
• 1256782-91-8 1-(4-((2-(4-methylpiperazin-1-yl)ethyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one 

Relevant articles and documents

Synthetic method of renal fibrosis resistant medicine 1-(substituted benzyl)-5- trifluoromethyl-2(1H)-pyridone hydrochloride

The invention relates to a synthetic method of a renal fibrosis resistant medicine 1-((4-(4-methyl piperazine-1-yl)amino)benzyl-5-trifluoromethyl-2(1H)-ketone hydrochloride(ZHC-116 hydrochloride). According to the invention, 2-chloro-5-trifluoromethylpyri

PREPARATION OF 1-(SUBSTITUTED BENZYL)-5-TRIFLUOROMETHYL-2(1H)PYRIDONE COMPOUNDS AND SALTS THEREOF AND THEIR APPLICATIONS

1-(substituted benzyl)-5-trifluoromethyl-2(1H)pyridone compounds and their pharmaceutical acceptable salts are disclosed. The preparation methods of the compounds and their salts and the use of the same for preparing the medicaments for treating fibrosis are also disclosed. New pyridine compounds and their salts are obtained from trifluoromethyl pyridone as starting material.