1256814-09-1

Basic information

• Product Name: N-cyclohexyl-1,5-dimethyl-3-oxido-1H-imidazole-4-carboxamide
• CAS NO: 1256814-09-1
• Molecular Weight: 237.302
• Mol File: 1256814-09-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-cyclohexyl-1,5-dimethyl-3-oxido-1H-imidazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexyl-1,5-dimethyl-3-oxido-1H-imidazole-4-carboxamide(1256814-09-1)
• EPA Substance Registry System: N-cyclohexyl-1,5-dimethyl-3-oxido-1H-imidazole-4-carboxamide(1256814-09-1)

Safety Data

• Hazardous Substances Data: 1256814-09-1(Hazardous Substances Data)

Upstream product

• 1100817-23-9 ethyl 1,5-dimethyl-3-oxido-1H-imidazole-4-carboxylate 
• 108-91-8 cyclohexylamine 

Relevant articles and documents

Synthesis and selected transformations of 3-oxido-1H-imidazole-4- carboxamides

An efficient synthesis of new N-alkyl- and N-aryl-3-oxido-1H-imidazole-4- carboxamides based on exploration of inexpensive, commercially available ethyl acetoacetate, paraformaldehyde and primary amines is described. Representative compounds were tested in selected transformations, such as 'sulfur-transfer reaction' leading to imidazole-2-thiones and isomerization to corresponding imidazol-2-ones. Strong intramolecular hydrogen bonding via the N-oxide function results in the reduced reactivity of 3-oxido-1H-imidazole-4-carboxamides in both reactions. Moreover, the palladium catalyzed C(2)-arylation of imidazole ring as well as azide-alkyne [3+2] cycloaddition using the N-propargyl substituted 4-carboxamide derived from an imidazole 3-oxide as a dipolarophile, were also studied.