1256842-47-3Relevant articles and documents
Microwave-assisted synthesis of polysubstituted 4-quinolones from deprotonated α-aminonitriles
Romek, Alexandra,Opatz, Till
experimental part, p. 5841 - 5849 (2011/01/04)
The α-alkylation of deprotonated N-aryl-α-aminonitriles with α-bromoesters furnishes intermediates that can be cyclized to 4-quinolones upon microwave irradiation. Alternatively, base-induced dehydrocyanation of the alkylation products furnishes enaminoes